子宫内膜异位症患者抗苗勒管激素基础水平研究进展

子宫内膜异位症(EMs)是育龄期妇女的常见病,包括腹膜型、深部结节型、卵巢型。EMs影响约2%的生殖期女性,约40%的EMs患者为卵巢型EMs,合并不孕者为40%~50%,并且具有易复发的特点。治疗方法包括药物保守治疗和手术治疗。近年来,有研究报道卵巢型EMs患者手术治疗后,卵巢功能下降,甚至出现卵巢功能早衰。而EMs本身,尤其是卵巢型EMs对卵巢储备功能的影响报道较少。抗苗勒管激素(AMH)是近年来评估卵巢储备功能的可靠标志物。通过分析3种不同类型EMs患者的AMH基础水平总结评价EMs对卵巢功能的影响,从而进一步指导临床工作。

Research Progress of Anti-Mullerian Hormone Levels in Patients with Endometriosis

Endometriosis (EMs) is a common disease in women of reproductive age,including three types:peritoneal type,deep-infiltration type and ovarian type.EMs is estimated to affect around 2％ of reproductive period women.Ovarian endometriomas are presented in 40％ of women with endometriosis,of which 40％-50％ are infertility and have the characteristics of a high relapse rate.The therapy includes drugs and surgery.In recent years,studies have reported the cystectomy of ovarian endometrioma may cause the decline of ovarian reserve and even premature ovarian failure,but endometriosis itself,especially the effect of ovarian endometriosis on ovarian reserve is rarely reported.Anti-Mullerian hormone (AMH) is a reliable marker of ovarian reserve in recent years.By analyzing the the AMH basal level in different types of endometriosis to evaluate the effect of endometriosis on ovarian reserve,so as to guide the clinical work.