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咽喉反流与儿童分泌性中耳炎
引用本文:赵靖,李艳珍,王桂香,张亚梅,倪鑫,张杰. 咽喉反流与儿童分泌性中耳炎[J]. 国际耳鼻咽喉头颈外科杂志, 2017, 41(3): 141. DOI: 10.3760/cma.j.issn.1673-4106.2017.03.005
作者姓名:赵靖  李艳珍  王桂香  张亚梅  倪鑫  张杰
作者单位:100045北京,首都医科大学附属北京儿童医院耳鼻咽喉头颈外科,儿童耳鼻咽喉头颈外科疾病北京市重点实验室
基金项目:北京市医院管理局重点医学专业发展计划-扬帆计划,北京市医院管理局临床医学发展专项-扬帆计划,Beijing Hospital Administration of Clinical Medicine Development Project-"Yang Fan" Program,Beijing Hospital Administration of Clinical Medicine Development Project-"Yang Fan" Program
摘    要:
咽喉反流是指胃内容物反流到食管上括约肌水平。分泌性中耳炎是儿童常见的疾病,可导致儿童听力损失和语言发育迟缓。近10年的研究支持咽喉反流与分泌性中耳炎有关系,但是咽喉反流引起分泌性中耳炎的确切病因机制尚未十分明确。本文对近期有关咽喉反流与儿童分泌性中耳炎相关性的文献进行检索与回顾,总结咽喉反流与儿童分泌性中耳炎相关性的最新进展。

关 键 词:咽喉反流  中耳炎  伴渗出液  胃蛋白酶原类  螺杆菌  幽门  

Laryngopharyngeal reflux and otitis media with effusion in children
Zhao Jing,Li Yanzhen,Wang Guixiang,Zhang Yamei,Ni Xin,Zhang Jie. Laryngopharyngeal reflux and otitis media with effusion in children[J]. International Journal of Otolaryngology-Head and Neck Surgery, 2017, 41(3): 141. DOI: 10.3760/cma.j.issn.1673-4106.2017.03.005
Authors:Zhao Jing  Li Yanzhen  Wang Guixiang  Zhang Yamei  Ni Xin  Zhang Jie
Abstract:
Laryngopharyngeal reflux (LPR) is defined as the reflux of gastric contents reaches the upper esophageal sphincter level.Otitis media with effusion (OME) is a common disease of children,inducing hearing loss and speech stunting.Studies performed over the last 10 years support the relationship between OME and LPR.The exact mechanism of LPR in the etiology of OME has not been clarified.We reviewed the recent literatures on the LPR and pediatric OME,and determined the new progress of the relationship between LPR and OME.
Keywords:laryngopharyngeal reflux  Otitis Media with Effusion  Pepsinogens  Helicobacter pylori
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