| 长链非编码RNA SNHG3在恶性肿瘤中的研究进展 |
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| 引用本文： | 郑志远(综述),曲国蕃(审校). 长链非编码RNA SNHG3在恶性肿瘤中的研究进展[J]. 实用肿瘤学杂志, 2021, 35(1): 50-54. DOI: 10.11904/j.issn.1002-3070.2021.01.010 |
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| 作者姓名： | 郑志远(综述) 曲国蕃(审校) |
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| 作者单位： | 哈尔滨医科大学附属肿瘤医院(哈尔滨 150081) |
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| 基金项目： | 海燕科研基金(编号:JJ2D2017-08)。 |
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| 摘 要： | 长链非编码RNA(Long non-coding RNA,lncRNA)是序列长度大于200个核苷酸且不能编码蛋白质的RNA分子.近年来,越来越多的研究指出lncRNA与肿瘤的诊断、预防、治疗及预后有密切联系,在恶性肿瘤的临床应用中有重大价值.小核仁RNA宿主基因3(Small nucleolar RNA host g...
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| 关 键 词： | 小核仁RNA宿主基因3 长链非编码RNA 恶性肿瘤 |
Research progress of long non-coding RNA SNHG3 in malignant tumor |
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| ZHENG Zhiyuan,QU Guofan. Research progress of long non-coding RNA SNHG3 in malignant tumor[J]. Journal of Practical Oncology, 2021, 35(1): 50-54. DOI: 10.11904/j.issn.1002-3070.2021.01.010 |
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| Authors: | ZHENG Zhiyuan QU Guofan |
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| Affiliation: | Harbin Medical University Cancer Hospital,Harbin 150081,China |
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| Abstract: | Long non-coding RNA(lncRNA)is a kind of RNA molecule whose sequence length is more than 200 nucleotides and cannot encode a protein.In recent years,more and more studies have pointed out that lncRNA is closely related to the diagnosis,prevention,treatment and prognosis of tumors,and has great value in the clinical application of malignant tumors.Small nucleolar RNA host gene-3(SNHG3)plays a carcinogenic role in promoting cell proliferation,invasion and regulating epithelial-mesenchymal transition(EMT),suggesting that SNHG3 can be used as a biomarker to evaluate the malignancy of tumors.This article reviews the research progress of the relationship between SNHG3 and malignant tumors in recent years,and discusses the current situation and prospects of SNHG3 in the treatment of malignant tumor. |
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| Keywords: | Small nucleolar RNA host gene-3 Long non-coding RNA Malignant tumor |
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