胸腺瘤48例临床病理的预后相关性研究

目的探讨胸腺上皮性肿瘤的临床病理特征及预后的关系。方法回顾性分析48例经我院外科治疗的胸腺瘤患者的临床资料，按WHO（2004年）胸腺肿瘤分类标准进行分类，根据临床和随访结果并对其预后与Masaoka临床分期等各因素进行相关性的研究。结果本组48例胸腺瘤的组织学分型：A型4例（8．3％），AB型3例（6．3％），B1型9例（18．8％），B2型8例（16．7％），B3型11例（22．9％），C型13例（27．1％）。临床分期：Ⅰ期12例（25．O％），Ⅱ期4例（8．3％），19期13例（27．1％），Ⅳ期19例（39．6％）。Ⅰ、Ⅱ、Ⅲ、Ⅳ期胸腺瘤切除术后3年生存率分别为100％、100％、68．3％、35．8％；5年生存率分别为66．5％、66．5％、39．7％、18．6％，并且患者的生存率与Masaoka临床分期密切相关，是胸腺瘤患者最重要的独立预后指标。结论Masaoka临床分期是影响胸腺瘤患者生存的最重要的预后参数．组织学分型和肿瘤是否完整切除是影响胸腺瘤患者术后毕存的雷兽因素。

Prognosis correlational study of 48 cses with thymoma pathology

Objective To study the relation of Clinicopathological characteristics and prognostic of thy-mic epithelial tumors. Methods To review and analyze the clinical data about 48 cases with thymic epithelial tumours were treated in surgery of our hospital,, according to the normal sort of WHO (2004 years) thymus tumor classification criteria to classify, according to the results of the clinical and follow-up and Masaoka clinical stage and prognosis, and other factors The relevance of the study. Results 48 cases of histological type of thymoma: A type for 4 cases(8.3%) ,AB type for 3(6.3%) ,B1 type for 9(18.8%) ,B2 type for 8(16.7%) ,B3 type for 11 cases(22.9% ) ,C type for 13 cases(27.1% ). Clinical staging: Ⅰ period of 12 cases(25.0% ), Ⅱ period of4 cases( 8.3% ), Ⅲ period of 13 cases(27.1% ), Ⅳ period of 19 cases(39. 6 percent). The results of follow-up data show that, Ⅰ,Ⅱ,Ⅲ,Ⅳ Thymectomy period after 3-year survival rates were 100% and 100% ,68.3%, 35.8% ;5-year survival rates were 66.5% and 66.5% ,39.7%, 18.6% and the survival rate of patients with Masaoka closely related to the clinical stage, patients with thymoma is the most important independent prognostic indicators. Conclusion Masaoka's clinical stage of survival in patients with thymoma is the most important prognostic parameters,type of tumor is complete excision is the impact on the survival of patients with thymoma an important factor.