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Comparative proteomic analysis of differentially expressed proteins in human pancreatic cancer tissue |
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| Authors: | Jian-Hua Chen Run-Zhou Ni Ming-Bing Xiao Ji-Guang Guo Jia-Wei Zhou |
| Affiliation: | Jian-Hua Chen,Run-Zhou Ni,Ming-Bing Xiao,Ji-Guang Guo , Jia-Wei Zhou Department of Gastroenterology,Affiliated Hospital of Nantong University,Nantong 226001,China,Institute of Neuroscience,Shanghai Institutes for Biological Sciences,Chinese Academy of Science,Shanghai 200030 |
| Abstract: | BACKGROUND:Pancreatic cancer is one of the most common malignant tumors.Early diagnosis of pancreatic cancer is difficult because of the latent onset and lack of good biomarkers.This study aimed to look for and identify differentially expressed proteins in tissues of pancreatic cancer and adjacent noncancerous tissues by proteomic approaches so as to provide information about possible pancreatic cancer markers and therapeutic targets.METHODS:Proteins extracted from 3 paired adjacent noncancerous and cancero... |
| Keywords: | electrophoresis gel two-dimensional pancreatic neoplasms proteomics |
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