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Primary Intramedullary Spinal Cord Germinoma: Case Report
Authors:Chute  Dennis J.  Burton  Eric C.  Klement  Ivan A.  Frazee  John G.  Vinters  Harry V.
Affiliation:(1) Department of Pathology and Laboratory Medicine, UCLA Medical Center, Los Angeles, USA;(2) Department of Neurosurgery, UCSF Medical Center, San Francisco, CA, USA;(3) Division of Neurosurgery, UCLA Medical Center, Los Angeles, USA
Abstract:
We describe an 18-year-old male with an intramedullary spinal cord germinoma in whom the diagnosis was made two years after onset of a progressive myelopathy. Spinal cord germinomas are rare, most having been described in young Japanese adults. They often respond well to radiotherapy. A unique feature of this case was the prolonged time interval between onset of the patient's symptoms and ability to visualize the mass radiographically. A further interesting finding was the infiltrative nature of the tumor surrounding residual spinal cord neurons.
Keywords:germinoma  immunohistochemistry  intramedullary tumor  spinal cord
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