| 应用伊曲康唑预防化疗后继发真菌感染的疗效 |
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| 摘 要： |
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| 关 键 词： | 恶性血液病 化学治疗 真菌感染 伊曲康唑 |
A controlled clinical trial of itraconazole for prevention of fungal infections secondary to chemotherapy. |
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| Chun-Yan Wang,Bing-Yi Wu,Kun-Yuan Guo. A controlled clinical trial of itraconazole for prevention of fungal infections secondary to chemotherapy.[J]. Journal of First Military Medical University, 2003, 23(4): 389-390 |
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| Authors: | Chun-Yan Wang Bing-Yi Wu Kun-Yuan Guo |
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| Affiliation: | Department of Hematology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. yanchunwa@yahoo.com.cn |
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| Abstract: | To study the preventive effect of itraconazole against fungal infections following chemotherapy in tumor patients, we conducted a double-blind randomized clinical trial in 114 tumor patients receiving chemotherapy, who were divided into itraconazole treatment group (n=52) and control group (n=62) and the incidences of fungal infections after chemotherapy were recorded. In comparison with the control group, itraconazole treatment group exhibited a significant decrease in fungal infection episodes (12.8% vs 3.8%), illustrating the efficacy of itraconazole treatment as a preventive measure against fungal infections secondary to chemotherapy. |
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