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参附脱毒胶囊联合丁丙诺啡舌下片治疗海洛因依赖的临床疗效观察
引用本文:刘期文,尹华,罗彦,赵晋平.参附脱毒胶囊联合丁丙诺啡舌下片治疗海洛因依赖的临床疗效观察[J].中国药物依赖性杂志,2004,13(2):121-123.
作者姓名:刘期文  尹华  罗彦  赵晋平
作者单位:1. 四川省德阳市公安局强制戒毒所,德阳,618000
2. 四川省德阳市精神卫生中心,德阳,618000
摘    要:目的 :探索戒毒疗效好、不造成新的药物成瘾 ,且经济的脱毒方案。方法 :将 80例海洛因依赖者分成A、B两组 ,A组给予参附脱毒胶囊联合丁丙诺啡脱毒 ,B组单纯使用小剂量美沙酮脱毒 ,对照观察两组的脱毒疗效。结果 :在控制戒断症状方面 ,A组与B组比较差异无显著性 (P >0 0 5 ) ,但A组不良反应轻微 ,B组有 2 3例停药后有索药行为。两药合用 ,参附脱毒胶囊用量减少。结论 :参附脱毒胶囊联合丁丙诺啡临床疗效可靠 ,无成瘾性 ,不良反应少 ,经济 ,值得推广使用

关 键 词:参附脱毒胶囊  丁丙诺啡片  美沙酮口服液  海洛因依赖  戒断症状
修稿时间:2003年12月16

ANTIMORPHPRO CAPSULE COMBINED WITH BUPRENORPHINE HYDROCHLORIDE SUBLINGUAL TABLETS FOR THE TREATMENT OF HEROIN DEPENDENCE
LIU Qiwen,YIN Hua,LUO Yan,ZHAO Jinping.ANTIMORPHPRO CAPSULE COMBINED WITH BUPRENORPHINE HYDROCHLORIDE SUBLINGUAL TABLETS FOR THE TREATMENT OF HEROIN DEPENDENCE[J].Chinese Journal of Drug Dependence,2004,13(2):121-123.
Authors:LIU Qiwen  YIN Hua  LUO Yan  ZHAO Jinping
Institution:LIU Qiwen1,YIN Hua1,LUO Yan2,ZHAO Jinping11
Abstract:Objective: To explore an effective and economic pharmaceutical therapy. Methods: 80 heroin addicts were divided into two groups and treated with Antimorphpro capsule combined with buprenorphine hydrochloride sublingual tablets (Group A) and methadone only (Group B). The results were compared. Results: In controlling withdrawal symptoms there was no significant difference (P<0.05) between the two groups. However, Group A experienced fewer and slighter adverse drug effects. The cost in Group A was reduced. 23 patients in Group B sought for methadone after administration stopped. Conclusion: Antimorphpro capsule combined with buprenorphine hydrochloride sublingual tablets can treat heroin dependence effectively with fewer adverse effects. No new dependence is produced. This method is fairly cheaper.
Keywords:Antimorphpro capsule  buprenorphine hydrochloride sublingual tablets  methadone  heroin dependence  withdrawal symptom
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