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神经精神性狼疮的临床表现和MRI特点分析
引用本文:杨燕,刘秀梅,孙美珍. 神经精神性狼疮的临床表现和MRI特点分析[J]. 中国神经免疫学和神经病学杂志, 2011, 18(4): 287-289. DOI: 10.3969/j.issn.1006-2963.2011.04.018
作者姓名:杨燕  刘秀梅  孙美珍
作者单位:1. 山西医科大学附属第一医院神经内科,030001
2. 山西医科大学附属第一医院风湿免疫科,030001
摘    要:
目的分析神经精神性狼疮(NPSLE)患者常见的临床表现并探讨其头颅MRI的特点及应用价值。方法回顾性分析11例经临床确诊的NPSLE患者的临床资料及头颅MRI检查结果。结果 11例患者中表现为狼疮样头痛8例,癫痫发作4例,言语不利3例,精神症状、视物模糊和偏瘫各2例,意识障碍和共济失调各1例。10例行头颅MRI检查的患者中,有6例出现异常信号影,病灶累及脑叶(额顶枕叶)3例,基底节2例,白质(皮质下白质、脑室旁及半卵圆中心)5例。病灶性质包括腔隙性梗死(4例)、脑血栓形成(3例)和脑萎缩(2例)。结论 NPSLE临床表现复杂多样,以狼疮样头痛及癫痫发作最常见;头颅MRI可发现NPSLE患者脑内病灶的部位及性质,是较为敏感的检查方法,结合临床可以协助诊断。

关 键 词:狼疮血管炎,中枢神经系统  磁共振成像

Analysis of common clinical manifestations and MRI findings in systemic lupus erythematosus patients with neuropsychiatric symptoms
YANG Yan,LIU Xiu-mei,SUN Mei-zhen. Analysis of common clinical manifestations and MRI findings in systemic lupus erythematosus patients with neuropsychiatric symptoms[J]. Chinese Journal of Neuroimmunology and Neurology, 2011, 18(4): 287-289. DOI: 10.3969/j.issn.1006-2963.2011.04.018
Authors:YANG Yan  LIU Xiu-mei  SUN Mei-zhen
Affiliation:YANG Yan,LIU Xiu-mei,SUN Mei-zhen*.*Department of Neurology,The First Affiliated Hospital of Shanxi Medical University,Taiyuan Shanxi 030001,China
Abstract:
Objective To analyze the common clinical manifestations of the neuropsychiatric systemic lupus erythematosus(NPSLE),and to investigate the features and the values of MRI findings.Methods Eleven cases of clinically confirmed NPSLE were retrospectively reviewed,their clinical information and MRI findings were analyzed.Results Of the 11 cases,there were eight different types of neuropsychiatric symptoms: lupus-like headache(8 cases),seizure(4 cases),speech disorder(3 cases),psychosis(2 cases),blurred vision(2 ...
Keywords:lupus vasculitis  central nervous system  magnetic resonance imaging  
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