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DCF和ECF方案治疗进展期胃癌的疗效观察
引用本文:梁冰,韩娜,杨家梅. DCF和ECF方案治疗进展期胃癌的疗效观察[J]. 中国肿瘤临床与康复, 2010, 0(1): 59-61
作者姓名:梁冰  韩娜  杨家梅
作者单位:郑州大学第二附属医院肿瘤科;
摘    要:
目的研究多西紫杉醇(希存)联合顺铂及5-Fu治疗进展期胃癌的近期疗效及不良反应。方法58例进展期胃癌患者随机分两组,DCF方案为治疗组(30例),ECF方案为对照组(28例)。结果DCF方案组有效率为36.6%(11/30),对照组有效率28.5%(8/28),两者差异无显著性(P〉0.05)。毒副反应主要表现为白细胞减少、恶心、呕吐和脱发,两组相比较差异无显著性。结论DCF方案治疗晚期胃癌疗效较好,毒副反应可耐受。

关 键 词:胃肿瘤/化学疗法  多烯紫杉醇  氟尿嘧啶  顺铂

Clinical study of comparative efficacy of DCF regimen vs. ECF regimen in treating advanced gastric cancer
LIANG Bing,HAN Na,YANG Jia-mei. Clinical study of comparative efficacy of DCF regimen vs. ECF regimen in treating advanced gastric cancer[J]. Chinese Journal of Clinical Oncology and Rehabilitation, 2010, 0(1): 59-61
Authors:LIANG Bing  HAN Na  YANG Jia-mei
Affiliation:LIANG Bing,HAN Na,YANG Jia-mei(Department of Oncology,The Second Affiliated Hospital of Zhenzhou University,Zhengzhou,Henan,450003,China)
Abstract:
Objective To evaluate the clinica1 efficacy and toxicity of docetaxo1 plus5Fu and cisplatin in the treatment of advanced gastric cancer.Methods Fifty-eight patients with advanced gastric cancer were randomly divided into 2groups.One group received docetaxol,5-Fu and cisplatin(DCF regimen,trial group),the other received epirubicin,5-Fu and cisplatin(ECF regimen,control group).Both regimens were repeated every 3 weeks.Results The tota1 response rate(CR + PR) was 36.6%(11 /30) in the trial group,and 28.5%(8 /2...
Keywords:Gastric neoplasms/chemotherapy  Docetaxo1  Fluorouracil  Cisplatin  
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