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管花肉苁蓉化学成分的研究
引用本文:宋志宏,莫少红,陈燕,屠鹏飞,赵玉英,郑俊华. 管花肉苁蓉化学成分的研究[J]. 中国中药杂志, 2000, 25(12): 728-730
作者姓名:宋志宏  莫少红  陈燕  屠鹏飞  赵玉英  郑俊华
作者单位:北京大学药学院天然药物学系,北京
摘    要:目的:研究国产管花肉苁蓉的化学成分。方法:采用各种色谱技术包括HPLC分离化学成分,根据理化性质和波谱数据鉴定结构。结果:分离得到4个环烯醚萜苷、1个木脂素苷和1个单萜,分别为五福花苷酸(Ⅰ),8-表马钱子酸(Ⅱ),京尼平苷酸(Ⅲ),玉叶金花苷酸(Ⅳ),丁香树脂酚葡萄糖苷(Ⅴ)和8-羟基香叶醇(Ⅵ)。结论:化合物Ⅰ和Ⅵ为首次从本属植物中分离得到,化合物Ⅲ,Ⅳ和Ⅴ为首次从本植物中分离得到。

关 键 词:列当科  肉苁蓉属  管花肉苁蓉  环烯醚萜苷
收稿时间:1999-11-18

Studies on Chemical Constituents of Cistanche tubulosa (Schenk) R. Wight
SONG Zhi hong,MO Shao hong,CHEN Yan,TU Peng fei,ZHAO Yu ying,ZHENG Jun hua [HT.,.]. Studies on Chemical Constituents of Cistanche tubulosa (Schenk) R. Wight[J]. China Journal of Chinese Materia Medica, 2000, 25(12): 728-730
Authors:SONG Zhi hong  MO Shao hong  CHEN Yan  TU Peng fei  ZHAO Yu ying  ZHENG Jun hua [HT.  .]
Affiliation:Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Abstract:OBJECTIVE: To investigate the chemical constituents of Cistanche tubulosa. METHOD: The chemical constituents were isolated by solvent extraction together with various chromatographic techniques including preparative HPLC. The structures were elucidated on the basis of chemical evidence and spectral data. RESULTS: Four iridoid glycosides, one lignan glycoside and one monoterpenoid were isolated from the 95% ethanol extract from the stem of C. tubulosa and identified as adoxosidic acid(I), 8-epiloganic acid(II), geniposidic acid (III), mussaenosidic acid(IV), (+)-syringaresinol-O-beta-D-gluco pyranoside(V) and 8-hydroxygeraniol(VI). CONCLUSION: Compounds I and VI were isolated from the genus of Cistanche for the first time. Compounds III, IV and V were isolated from this plant for the first time.
Keywords:Orobanchacae  Cistanche  Cistanche tubulosa  iridoid glycosides
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