Ophthalmopathology in rats with MBP-induced experimental autoimmune encephalomyelitis |
| |
| Authors: | Oliver W. Gramlich Stephanie C. Joachim Philip F. Gottschling Panagoitis Laspas Clemens S. Cuny Norbert Pfeiffer Franz H. Grus |
| |
| Affiliation: | 1.Experimental Ophthalmology, Department of Ophthalmology, University Medical Center,Johannes Gutenberg University Mainz,Mainz,Germany;2.Center for Vision Science,Ruhr University Eye Hospital,Bochum,Germany |
| |
| Abstract: | Purpose Multiple studies indicate that T-cells play a major role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis, but recently an involvement of antibodies has also been discussed. The aim of our study was to examine the effects of myelin basic protein (MBP) immunization on survival of neurons, alteration of antibody reactivity, and microglia in the retinal ganglion cell layer. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
