| 心脉通胶囊对急性心肌梗塞患者血管内皮生长因子表达的影响 |
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| 引用本文： | 孟君,冯君,丘瑞香,蓝军,贺敬波. 心脉通胶囊对急性心肌梗塞患者血管内皮生长因子表达的影响[J]. 广州中医药大学学报, 2002, 19(2): 88-90 |
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| 作者姓名： | 孟君 冯君 丘瑞香 蓝军 贺敬波 |
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| 作者单位： | 中山医科大学附属第一医院中医科,广州,510080;广东东莞石龙人民医院心内科,广东东莞,523321;广东深圳宝安区人民医院中医科,深圳,518000 |
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| 摘 要： | [目的]探讨中药复方心脉通胶囊(由人参、三七、大黄、枳壳等组成)对急性心肌梗塞(AMI)患者血管内皮生长因子(VEGF)表达的影响。[方法]46例急性心肌梗塞患者随机分为心脉通胶囊组(23例,常规西药加心脉通胶囊治疗)与对照组(23例,常规西药治疗),观察治疗前后治疗组及对照组患者冠状动脉成形术(PTCA)前和术后不同时间点血清VEGF水平变化。[结果]两组患者血清VEGF水平在1周后存在显著性差异(P<0.05)。[结论]心脉通胶囊有促血循环中VEGF表达的作用,可能具有诱导新生血管形成的作用。
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| 关 键 词： | 心脉通胶囊/治疗应用 心肌梗塞/中西医结合疗法 血管内皮生长因子 |
| 文章编号： | 1007-3213(2002)02-0088-04 |
| 修稿时间： | 2002-01-15 |
Effect of Xinmaitong Capsule on Serum Level of Vascular Endothelial Growth Factor |
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| MENGJun,FENG Jun,QIU Ruixiang,LAN Jim,HE Jingbo. Effect of Xinmaitong Capsule on Serum Level of Vascular Endothelial Growth Factor[J]. Journal of Guangzhou University of Traditional Chinese Medicine, 2002, 19(2): 88-90 |
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| Authors: | MENGJun FENG Jun QIU Ruixiang LAN Jim HE Jingbo |
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| Abstract: | [ Objective] To explore the effect of Xinmaitong capsule on the expression of vascular endothelial growth factor (VEGF) in patients with acute myocardial ischemia (AMI). [Methods] Forty-six cases of AMI were randomly allocated to Group A (n = 23, treated with routine treatment combined with Xinmaitong capsule) and Group B (n = 23 cases, only routine treatment) . Serum VEGF level in different time before and after percutaneous transluminal coronary angio-plasty (PTCA) was examined. [Results] There is a significant difference between two groups. Serum VEGF level in Group A after a week of treatment differed that in Group B (P < 0.05). [Conclusion] Xinmaitong capsule can promote the expression of VEGF and induce neo-vascular formation. |
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| Keywords: | XINMAITONG CAPSULE/ther. use MYOCARDIAL INFARCTION/TCM-WM therapy VASCULAR ENDOTHELIAL GROWTH FACTOR |
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