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| 射波刀与经肝动脉化疗栓塞治疗原发性肝癌 | |
| 引用本文： | 赵毅峰,杨生虎,张萍. 射波刀与经肝动脉化疗栓塞治疗原发性肝癌[J]. 肝胆外科杂志, 2019, 27(1): 50-53 |
| 作者姓名： | 赵毅峰 杨生虎 张萍 |
| 作者单位： | 青海大学附属医院,西宁,810001;青海大学附属医院,西宁,810001;青海大学附属医院,西宁,810001 |
| 摘 要： | 目的观察射波刀与经肝动脉化疗栓塞(TACE)治疗对原发性肝癌患者近期疗效、生活质量、血清肿瘤标志物及不良反应的影响。方法选取2014年1月～2017年1月我院收治的96例原发性肝癌患者,按照入院顺序单双号分为2组,各48例,对照组采取TACE疗法,观察组采取TACE联合射波刀方案,比较2组治疗前后生活质量指数(QOL)评分、血清肿瘤标志物[E-钙蛋白(EC)血管内皮生长因子(VEGF)、基质金属蛋白酶(MMP)]、不良反应情况,并观察2组近期疗效。结果观察组治疗后1个月复查显示,治疗总有效率75. 00%,明显高于对照组54. 17%(P <0. 05);治疗后2周,观察组QOL评分明显优于对照组(P <0. 05),血清EC、VEGF、MMP水平明显低于对照组(P <0. 05);观察组不良反应总发生率33. 33%,对照组31. 25%,2组比较无明显差异(P> 0. 05)。结论 TACE联合射波刀可有效提高原发性肝癌近期疗效,降低血清肿瘤标志物水平,改善生活质量,且无严重不良反应。 |
| 关 键 词： | 原发性肝癌 射波刀 经肝动脉化疗栓塞 近期疗效 生活质量 |
Effect of cyberknife and transcatheter arterial chemoembolization on short-term efficacy,quality of life,serum tumor markers and adverse reactions in patients with primary liver cancer |
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| ZHAO Yi-feng,YANG Sheng-hu,ZHANG Ping. Effect of cyberknife and transcatheter arterial chemoembolization on short-term efficacy,quality of life,serum tumor markers and adverse reactions in patients with primary liver cancer[J]. Journal of Hepatobiliary Surgery, 2019, 27(1): 50-53 | |
| Authors: | ZHAO Yi-feng YANG Sheng-hu ZHANG Ping |
| Affiliation: | (Department of interventional medicine, Affiliated Hospital of Qinghai University, Xining 810001, China) |
| Abstract: | ZHAO Yi-feng;YANG Sheng-hu;ZHANG Ping(Department of interventional medicine, Affiliated Hospital of Qinghai University, Xining 810001, China) |
| Keywords: | primary liver cancer cyber knife transcatheter arterial chemoembolization short-term efficacy quality of life |
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