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气道高反应性患者肺功能特点分析
引用本文:张霖,聂秀红,任魁,高赏. 气道高反应性患者肺功能特点分析[J]. 临床肺科杂志, 2011, 16(8): 1186-1187
作者姓名:张霖  聂秀红  任魁  高赏
作者单位:首都医科大学宣武医院呼吸科,北京,100053
摘    要:目的探讨气道高反应患者肺功能特点。方法 220例慢性咳嗽或胸闷患者按支气管激发试验(BPT)结果分阳性组118例,阴性组102例,比较肺功能指标在吸入生理盐水前后的差异。结果阳性组FEV1、FEV1/FVC、FEF 25%、FEF50%、FEF 75%、MMEF较阴性组明显降低(P〈0.01),吸入生理盐水后阳性组FVC、FEV1、FEF50%及MMEF较阴性组有明显下降(P〈0.05)。Logistic回归显示小气道病变及吸入生理盐水后的△FEV1是BPT阳性结果的危险因素。结论气道高反应患者具有大小气道功能异常特点。小气道病变及吸入生理盐水后FEV1下降率高的患者更易有BPT阳性结果。

关 键 词:气道高反应性  支气管激发试验  第1秒用力呼气容积  小气道病变

Characteristics of pulmonary function on patients with airway hyper-responsiveness
ZHANG Lin,NIE Xiu-hong,REN Kui,GAO Shang. Characteristics of pulmonary function on patients with airway hyper-responsiveness[J]. Journal of Clinical Pulmonary Medicine, 2011, 16(8): 1186-1187
Authors:ZHANG Lin  NIE Xiu-hong  REN Kui  GAO Shang
Affiliation:ZHANG Lin,NIE Xiu-hong,REN Kui,GAO Shang Department of Respiratory Medicine,Xuanwu Hospital of Capital Medical University,Beijing 100053,China
Abstract:Objective To investigate the characteristics of ventilation function in patients with airway hyper-responsiveness(AHR).Methods 220 cases with complaint of chronic cough or chest tightness were divided into positive group(118 cases) and negative group(102 cases) according to the bronchial provocation test(BPT).Ventilation function was measured before and after inhaling 0.9% saline and compared between the groups.Results The baseline FEV1,FEV1/FVC,FEF25%,FEF50%,FEF75%,MMEF were significantly decreased(all P<0...
Keywords:airway hyper-responsiveness  bronchial provocation tests  forced expiratory volume in one second  Small airway dysfunction  
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