| 硅凝胶人工晶体的生物相容性 |
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| 引用本文： | 吴德敏 雷远卿. 硅凝胶人工晶体的生物相容性[J]. 生物医学工程学杂志, 1991, 8(1): 33-38 |
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| 作者姓名： | 吴德敏 雷远卿 |
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| 作者单位： | 四川省劳动卫生职业病防治研究所(吴德敏)，四川省劳动卫生职业病防治研究所(雷远卿) |
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| 摘 要： | 本文参照国内外有关医用高分子材料的生物学评价试验方法,对国产医用级硅凝胶人工晶体作了系统的生物学评价。结果表明:硅凝胶人工晶体对眼及皮肤无刺激作用、无热原、无毒性、体外溶血率小于5％,对细胞生长有促进作用,长期植入皮下时,随植入时间延长,囊壁厚度逐渐变薄,炎性细胞反应30天基本消失。染色体及骨髓多染红细胞未受影响。因此,可以认为硅凝胶人工晶体有良好的生物相容性。
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| 关 键 词： | 人工晶本 溶血 硅凝胶 生物相容性 |
The Biocompatibility of Artificial Lens of Silicone Rubber |
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| Wu Demin,Lei Yuanqing The Provincial Institute of Labour Hygiene and Occupational Disease,Chengdu. The Biocompatibility of Artificial Lens of Silicone Rubber[J]. Journal of biomedical engineering, 1991, 8(1): 33-38 |
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| Authors: | Wu Demin Lei Yuanqing The Provincial Institute of Labour Hygiene Occupational Disease Chengdu |
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| Abstract: | The toxicity of artificial siliconelens was studied. The results showedthat it contained no toxic componentspermeating through the body. Noirritation was observed with any ofits extracts, and none of its componentswere found to be pyrogenic. Theheamolysis rate was no more than5%; growth rate of L_(929) cells andheamopoietic stem cell cultures showedstimulation. Chrosmosomal aberrationrate and micronuclei rate of bonemorrow erythrocytes were notincreaed. Short and long time subcu-taneous implantation of these lensesshowed acceptable tissue compatibilityand good biocompatibility. |
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| Keywords: | Artificial lenses Silicone rubber Heamolysis Biocompatibility |
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