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Sepsis of a prosthetic joint and biological therapies

Authors:	Fernández-Castro M Andreu J L Muñoz P Silva L

Affiliation:	Department of Rheumatology, Hospital Universitario Puerta de Hierro, Madrid, Spain

Abstract:	SIR, We read with interest the article of Ledingham and Deighton[1] updating the guidelines for prescribing TNF- ${alpha}$ blockers inadults with rheumatoid arthritis. The guidelines establish thatthe sepsis of a prosthetic joint that remains in situ is animportant exclusion criterion for

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