The NIF LinkOut Broker: A Web Resource to Facilitate Federated Data Integration using NCBI Identifiers |
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Authors: | Luis Marenco Giorgio A Ascoli Maryann E Martone Gordon M Shepherd Perry L Miller |
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Institution: | (1) Department of Anesthesiology, Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06520-8009, USA;(2) Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06520, USA;(3) Department of Molecular, Cellular, and Developmental Biology, Yale University School of Medicine, New Haven, CT 06520, USA;(4) Center for Neural Informatics, Structure, and Plasticity, Molecular Neuroscience Department, Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA;(5) Department of Neurosciences, University of California, San Diego, CA 92092, USA |
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Abstract: | This paper describes the NIF LinkOut Broker (NLB) that has been built as part of the Neuroscience Information Framework (NIF)
project. The NLB is designed to coordinate the assembly of links to neuroscience information items (e.g., experimental data,
knowledge bases, and software tools) that are (1) accessible via the Web, and (2) related to entries in the National Center
for Biotechnology Information’s (NCBI’s) Entrez system. The NLB collects these links from each resource and passes them to
the NCBI which incorporates them into its Entrez LinkOut service. In this way, an Entrez user looking at a specific Entrez
entry can LinkOut directly to related neuroscience information. The information stored in the NLB can also be utilized in
other ways. A second approach, which is operational on a pilot basis, is for the NLB Web server to create dynamically its
own Web page of LinkOut links for each NCBI identifier in the NLB database. This approach can allow other resources (in addition
to the NCBI Entrez) to LinkOut to related neuroscience information. The paper describes the current NLB system and discusses
certain design issues that arose during its implementation. |
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Keywords: | Data integration Entrez LinkOut Gateway GUID Neurodatabases PubMed |
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