自身免疫性肝炎合并淋巴结肿大14例分析

目的分析自身免疫性肝炎（autoimmunehe patitis，AIH）合并淋巴结肿大的临床特点及探讨可能形成原因。方法回顾性分析2000年1月～2008年1月在天津医科大学总医院确诊的114例AIH患者的临床资料。结果114例A1H患者分为两组，其中A组无淋巴结肿大100例，B组合并淋巴结肿大14例，二者对比分析。A、B两组比较，B组易出现肝硬化（57／100vs12／14，P〈0．05），两组白细胞、血小板差异有统计学意义（P〈0．05）。结论AIH可合并淋巴结肿大，且合并淋巴结肿大者较易出现肝硬化，表现脾功能亢进，可能是AIH预后不良的一个指标。

Autoimmune hepatitis with lymphadenectasis:a study of 14 cases

Objective To analyze the clinical features of patients with lymphadeneetasis and to discuss the possible mechanism. Methods One hundred and fourteen cases with autoimmune hepatitis were collected and analyzed retrospectively in Tianjin Medical University General Hospital from-Jan, 2000 to Jan, 2008. Results They were divided into two groups：group A didn＇ t complicated with lymphadeneetasis, while group B complicated with lymphadenectasis. Patients of group B were more easily to develop into cirrhosis than those of group A（57/100 vs 12/14,P 〈 0.05）. There was statistical significance in leucocytes and platelets of these 2 groups （P 〈 0.05）. Conclusion AIH can complicate with lymphadenectasis, which appeare cirrhosis and hypersplenia more easily and it may be with unfavorable prognosis.