工娱疗合并利培酮治疗精神分裂症阴性症状自身对照研究

目的：探讨工娱疗合并非典型抗精神病药(维思通)对精神分裂症阴性症状的治疗及康复作用。方法：对30例以阴性症状为主的精神分裂症患，虽用利培团治疗足够剂量和足够疗程仍存在有明显阴性症状的病人，在不改变用药量的前提下，合并工娱疗；用PANSS和住院病人康复疗效评定量表(IPROS)作为评定工具对工娱疗前后作自身对照。结果：合并工娱疗8周后病人PANSS总分进一步改善，尤其阴性症状因子改善明显；社会功能明显改善。结论：工娱疗合并维思通进一步改善精神分裂症阴性症状并促进社会功能恢复。

A Self-controlled study of the negative symptoms of schizophrenia treated by risperidon with occupational and recreational therapy

Objective:To investiga te the effect of risperidong combi ned with occupational and recreati onal therapy on the negative sympt oms of schizophrenia Methods: 30 schizophrenic pati ents with mainly negative symptoms ,who still had some evident symptom s after the treatment by risperido ne with enough does and course,wer e treated by occupational and recr eational therapy combined with res peridion (the same chose) the clin ical efficacy was assessed with PA NSS and IPROS.Result:The total sco re of PANSS was further decreased at the end of the 8th week after c ombined therapy The scores of the negative symptoms and social funct ion were apparently different Conc lusion:Occupationed recreational t herapy combined with risperidone c ould be better in the improvement of the negative sympotoms of schi zophrenia and the restoration of the social function.