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人血白蛋白在治疗急性重症缺血性卒中中的疗效观察
引用本文:孙奉辉,李淑娟,刘岳阳,杨磊,胡文立. 人血白蛋白在治疗急性重症缺血性卒中中的疗效观察[J]. 中国卒中杂志, 2009, 4(12): 951-955
作者姓名:孙奉辉  李淑娟  刘岳阳  杨磊  胡文立
作者单位:北京市首都医科大学附属北京朝阳医院神经内科
摘    要:目的 观察人血白蛋白治疗急性重症缺血性卒中的疗效。方法 收集急性重症缺血性卒中患者80例,分为两组。治疗组44例,在常规治疗的基础上加用20%人血白蛋白50ml静脉滴注2次/d,连用5d,之后酌情间断应用;对照组36例,仅在血清白蛋白低于25g/L时加用人血白蛋白。比较治疗前、治疗2周后两组间神经功能缺损程度评分和Glasgow昏迷评分的变化,以及治疗期间两组间并发症的发生率。结果 治疗组神经功能缺损评分明显低于对照组(P<0.05),而Glasgow昏迷评分明显高于对照组(P<0.05);治疗组肺部感染、肾功能不全、应激性溃疡、低蛋白血症等并发症的发生率均明显低于对照组(P<0.05)。结论 人血白蛋白治疗急性重症缺血性卒中的疗效显著,且能降低重症缺血性卒中患者并发症的发生率。

关 键 词:脑梗死  白蛋白  治疗结果  并发症  
收稿时间:2009-08-02
修稿时间:2009-07-02

Observation of the Effect of Human Albumins in Acute Severe Cerebral Infarction Patients
SUN Feng-Hui,LI Shu-Juan,LIU Yue-Yang,et al.. Observation of the Effect of Human Albumins in Acute Severe Cerebral Infarction Patients[J]. Chinese Journal of Stroke, 2009, 4(12): 951-955
Authors:SUN Feng-Hui  LI Shu-Juan  LIU Yue-Yang  et al.
Affiliation:SUN Feng-Hui, LI Shu-Juan, LIU Yue-Yang, et al.
Abstract:Objective To appraise the effect of Human Albumins in the acute severe cerebral infarction patients.
Methods Eighty acute severe cerebral infarction patients were divided into 2 groups. Conventional therapy was applied in the 2 groups, and Human Albumins was used conventionally in treatment group(n=44), whereas it was used in control group(n=36) only when serum albumin was less than 25g/L. Following treatment for 2 weeks, Scandinavian Stroke Scale and Glasgow Coma Scale were evaluated, and the incidence of complications was compared in the 2 groups.
Results After treatment, clinical neurologic impairment score of treatment group was significantly lower than that of control group(P〈0.05). Coma scale of treatment group was significantly higher than that of control group(P〈0.05). The incidence of complications, such as pulmonary infection, renal dysfunction, stress, ulcer and hypoproteinemia, was all higher than that of control group(P〈0.05).
Conclusion Human Albumins was significant effective for acute severe cerebral infarction patients and could decrease the incidence of complications of severe cerebral infarction patients.
Keywords:Brain infarction Albumins Treatment outcome complication
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