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甲状腺素对大鼠膈肌影响的酶组织化学研究
引用本文:于向民,王彦. 甲状腺素对大鼠膈肌影响的酶组织化学研究[J]. 青岛大学医学院学报, 1990, 0(4)
作者姓名:于向民  王彦
作者单位:青岛医学院组织胚胎学教研室(于向民),中国医科大学组织胚胎学教研室(王彦)
摘    要:
采用酶组织化学方法和显微图像分析技术,观察甲状腺素对大鼠膈肌肌纤维及其运动终板的影响.结果表明,甲状腺素可引起3种肌纤维运动终板不同程度的乙酰胆碱酯酶(AchE)活性降低,含量减少,终板面积缩小;肌纤维琥珀酸脱氢酶(SDH)含量减少,肌纤维直径缩小.并对其发生机理进行了初步探讨.

关 键 词:甲状腺素  运动终板  肌纤维  乙酰胆碱酯酶  琥珀酸脱氫酶  大鼠

HISTOCHEMICAL STUDY OF EFFECT OF THYROXINE ON RAT DIAPHRAM
Yu Xiangmin,Wang Yan. HISTOCHEMICAL STUDY OF EFFECT OF THYROXINE ON RAT DIAPHRAM[J]. Acta Academiae Medicinae Qingdao Universitatis, 1990, 0(4)
Authors:Yu Xiangmin  Wang Yan
Affiliation:Yu Xiangmin,Wang Yan Department of Histology and Embryoloy
Abstract:
The effect of thyroxine on the disphram muscle fibers and motor end-plates in the rat was investigated by using histochemistry and microsphotometry. The result showed that thyroxine induced a weakening of AchE activity, a decrease In AchE content and a reduciton of the end-plate area in the motor end-plates of three types of muscle fiber, in varying degrees. It also caused a decrease in SDH content and a reduction of fiber diameter in the three types of muscle fiber. The genetic mechanism is discussed.
Keywords:Thyroxine  Motor end-plate  Muscle fiber  Acetylcholinesterase  Succinate dehydrigenase  Rats
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