The temperature dependence of electrical coupling in the organ of Corti |
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| Authors: | J Santos-Sacchi |
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| Affiliation: | 1. Electrochemical Sensors Research Laboratory, Department of Chemistry, Faculty of Science, Shahid Rajaee Teacher Training University, Tehran, Iran;2. Thin Layer and Nanotechnology Laboratory, Department of Chemical Technologies, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran;3. Department of Chemistry, University of Zanjan, Zanjan, Iran;4. Department of Chemistry, Isfahan University of Technology, Isfahan, Iran;5. School of Resources and Environment, University of Electronic Science and Technology of China, 611731, Xiyuan Ave, Chengdu, PR China;6. Department of Electricity and Energy, Vocational School of Technical Sciences, Akdeniz University, Antalya 07070, Turkey;7. School of Engineering, Lebanese American University, Byblos, Lebanon;8. “Cristofor Simionescu” Faculty of Chemical Engineering and Environmental Protection, “Gheorghe Asachi” Technical University, Bld. D. Mangeron no 73, 700050, Iasi, Romania;9. State Key Laboratory of Multiphase Flow in Power Engineering, Xi''an Jiaotong University, Xi''an, Shaanxi 710049, PR China;10. Department of Chemistry, University Centre for Research & Development, Chandigarh University, Mohali-140413, Punjab, India;1. Dalian University of Technology, School of Automotive Engineering, State Key Lab of Structural Analysis for Industrial Equipment, Dalian 116024, China;2. Hefei University of Technology, Industrial and Equipment Technology Institute, Hefei 230601, China |
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| Abstract: | Electrical coupling in an in vitro preparation of the organ of Corti was evaluated during changes in temperature of the bathing media. The effect of cooling the organ from 35 +/- 2 degrees C to 17 +/- 3 degrees C is to reduce membrane potentials, increase input resistance and decrease coupling ratios. Decreases in coupling ratios ranging from 15 to 75% have been observed. The effects are reversible upon warming. Membrane potentials are very susceptible to depolarization caused by cooling. The reduction in coupling is not due to depolarization nor is it dependent upon extracellular Ca2+. It is conceivable, however, that intracellular stores of Ca2+ are released or that intracellular pH is altered. |
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