合并糖尿病的冠心病患者冠状动脉粥样硬化与颈动脉粥样硬化的关系

目的探讨合并糖尿病的冠心病患者颈动脉粥样硬化与冠状动脉粥样硬化的关系.方法通过对73例合并2型糖尿病的冠心病患者行冠状动脉造影明确冠状动脉病变,同时行颈动脉超声检查,检测颈动脉内膜-中膜厚度.结果不同支数冠状动脉病变者之间比较,颈动脉内膜-中膜厚度、颈动脉斑块积分和斑块发生率差异有显著性(分别为P＜0.001、P＜0.005、P＜0.01).冠状动脉病变支数与颈动脉内膜-中膜厚度和颈动脉斑块积分有明显的相关性,其相关系数分别为0.71和0.68(P＜0.001).冠状动脉造影积分与颈动脉内膜-中膜厚度及颈动脉斑块积分相关系数分别为0.69和0.66(P＜0.001).结论合并糖尿病冠心病患者颈动脉粥样硬化与冠状动脉粥样硬化存在显著的正相相关性,这类患者通过了解颈动脉病变可间接反映冠状动脉粥样硬化病变.

Relationship between Carotid Atherosclerosis and Coronary Atherosclerosis in Patients of Coronary Heart Disease Complicated with Diabetes Mellitus

Aim To observe the relationship between carotid atherosclerosis (CAs) and coronary arterial atherosclerosis (CAAs) in patients complicated with diabetes mellitus (DM). Methods Coronary arteriography was performed in 73 patients with diabetes mellitus to judge the degree of CAAs. The carotid intima-media thickness(IMT) and carotid plaques were measured by ultrasound. Results There was significant difference between CAAs group with DM in IMT, carotid plaques score and incidence of carotid atherosclerosis plaques (P<0.001,P<0.005,P<0.01). There was positive correlation between rami of CAAs with DM and IMT, carotid atherosclerosis score (r=0.71,0.68, P<0.001). There was positive correlation between coronary arteriography score and IMT, carotid atherosclerosis score (r=0.69, 0.66, P<0.001). Conclusion There was close relationship between CAs and CAAs in patients of coronary heart disease complicated with diabetes mellitus.