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Modified In Vivo Lung Perfusion for Local Chemotherapy: A Preclinical Study With Doxorubicin
Authors:Pedro Reck dos SantosJin Sakamoto  MD  Manyin ChenVirginia Linacre  MD  Chantel ArceMingyao Liu  MD  MS  Thomas K. WaddellShaf Keshavjee  MD  MS  Marcelo Cypel
Affiliation:Latner Thoracic Surgery Research Laboratories, Toronto General Research Institute; and Division of Thoracic Surgery, Department of Surgery, University of Toronto, University Health Network, Toronto, Ontario, Canada
Abstract:
Keywords:ALI, acute lung injury   ANOVA, analysis of variance   BSA, body surface area   Dox, doxorubicin   ELISA, enzyme-linked immunosorbent assay   EVLP, ex   vivo lung perfusion   HPLC, high performance liquid chromatography   Ifos, ifosfamide   IL1-ß  , interleukin one-beta   IL-6, interleukin six   IL-8, interleukin eight   IVLP, in   vivo lung perfusion   PAP, pulmonary artery pressure   PawP, peak airway pressure   P/F ratio, partial pressure of oxygen divided by the fraction of inspired   TNFα, tumor necrosis factor &ndash   alfa
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