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短暂性脑缺血发作与脂蛋白(a)和D-二聚体的关系
引用本文:庄伟端,许端敏,郑璇.短暂性脑缺血发作与脂蛋白(a)和D-二聚体的关系[J].中国动脉硬化杂志,2004,12(1):100-101.
作者姓名:庄伟端  许端敏  郑璇
作者单位:1. 汕头大学医学院附属第一医院神经内科,广东省汕头市,515041
2. 汕头大学医学院附属第一医院心内科,广东省汕头市,515041
摘    要:探讨短暂性脑缺血发作与脂蛋白 (a)及D 二聚体的关系。测定 4 8例短暂性脑缺血发作患者发病 2 4h内血清脂蛋白 (a)和血浆D 二聚体水平 ,并与 2 5例健康正常人对照。结果发现 ,短暂性脑缺血发作患者脂蛋白 (a)和D 二聚体水平明显高于对照组 (P <0 .0 5 ) ;脂蛋白 (a)水平与D 二聚体呈正相关 (P <0 .0 1) ;短暂性脑缺血发作伴有梗死灶者脂蛋白 (a)和D 二聚体水平均高于无梗死灶者 (P <0 .0 5 )。提示脂蛋白 (a)及D 二聚体水平升高在短暂性脑缺血发作的发生发展中起一定作用。

关 键 词:神经病学  D-二聚体和脂蛋白(a)的作用  生物化学分析法  短暂性脑缺血发作  脂蛋白(a)
文章编号:1007-3949(2004)12-01-0100-02
收稿时间:2003/7/17 0:00:00
修稿时间:2003年7月17日

Study on the Interrelationship Between Serum Lipoprotein(a) and Plasma D-dimer and Transient Ischemic Attack
ZHUANG Wei-Duan,XU Duan-Min,and ZHENG Xuan.Study on the Interrelationship Between Serum Lipoprotein(a) and Plasma D-dimer and Transient Ischemic Attack[J].Chinese Journal of Arteriosclerosis,2004,12(1):100-101.
Authors:ZHUANG Wei-Duan  XU Duan-Min  and ZHENG Xuan
Institution:Department of Neurology of the First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong 515041, China
Abstract:Aim To investigate the relationships between transient ischemic attack (TIA) and serum lipoprotein(a) and plasma D-dimer. Methods The serum levels of lipoprotein(a) and the plasma levels of D-dimer were measured in 48 patients with TIA within 24 hours. 25 healthy were set as control group. Results The levels of lipoprotein(a) and D-dimer in patients with TIA were higher than control group (P<0.05). In TIA group, the levels of lipoprotein(a) and D-dimer in those patients with infarction significantly increased compared with those without infarction (P<0.05). Conclusions These results suggest that increased lipoprotein(a) and D-dimer may play roles in the formation of TIA.
Keywords:Transient Ischemic Attack  Lipoprotein(a)  D-dimer  Atherosclerosis  Infarction
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