经肺腧穴中药离子导入联合振动排痰治疗慢性阻塞性肺疾病急性加重期临床疗效

目的:探讨经肺腧穴中药离子导入联合振动排痰干预慢性阻塞性肺疾病急性加重期(AECOPD)的临床疗效。方法:将62例AECOPD患者随机分为对照组和观察组,每组31例,对照组给予振动排痰干预,观察组基于以上加予经肺腧穴中药离子导入干预,观察两组干预前及干预14 d后的中医症状体征积分,评估两组临床疗效,对比两组干预前及干预14 d后的临床观察指标和生活质量。结果:干预后,两组喘息、咳嗽、咯痰及湿罗音评分显著降低(P<0.05),观察组显著高于对照组(P<0.05); 观察组总有效率显著高于对照组(96.77%与80.65%,P<0.05); 干预后,两组动脉血氧分压(PaO₂)值显著提高(P<0.05),日排痰量显著增加(P<0.05),呼吸困难指数Borg(Borg Scale)量表显著下降(P<0.05),观察组变化幅度显著大于对照组(P<0.05),观察组住院时间显著短于对照组(P<0.05); 干预后,两组简化St George's呼吸问卷(SGRQ)量表关于症状、活动、疾病影响3个维度评分及总分显著降低(P<0.05),观察组变化幅度显著大于对照组(P<0.05)。结论:经肺腧穴中药离子导入联合振动排痰干预AECOPD患者疗效确切,可有效改善其症状体征、肺部血氧供应和气道呼吸困难,有助于提高其生活质量。

Clinical efficacy of Chinese medicine iontophoresis via Feishu point combined with vibration sputum discarding in the treatment of AECOPD

Objective:To explore the clinical efficacy of Chinese medicine iontophoresis via Feishu point combined with vibration sputum discarding in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:62 patients with AECOPD were randomly divided into control group and observation group,with 31 cases in each group.Control group was given vibration sputum discarding intervention,and observation group was given Chinese medicine iontophoresis via Feishu point based on the above intervention.The scores of TCM symptoms and signs were observed in the two groups before intervention and after 14 d of intervention.The clinical efficacy of the two groups was evaluated.The clinical observation indicators and quality of life were compared between the two groups before intervention and after 14 d of intervention.Results:After intervention,the scores of wheezing,cough,expectoration and wet rales in the two groups were significantly decreased(P<0.05),and the scores in observation group were significantly higher than those in control group(P<0.05).The total effective rate in observation group was significantly higher than that in control group(96.77%vs 80.65%)(P<0.05).After intervention,the arterial partial pressure of oxygen(PaO2)was significantly increased(P<0.05),and the daily sputum excretion volume was significantly increased(P<0.05),and the dyspnea index Borg(Borg Scale)score was significantly decreased(P<0.05),and the changes in observation group were significantly greater than those in control group(P<0.05),and the hospital stay in observation group was significantly shorter than that in control group(P<0.05).After intervention,the scores of three dimensions of symptoms,activities and disease influence and the total score of simplified St George’s Respiratory Questionnaire(SGRQ)scale were significantly reduced in the two groups(P<0.05),and the changes in observation group were significantly greater than those in control group(P<0.05).Conclusion:Chinese medicine iontophoresis via Feishu point combined with vibration sputum discarding has exact efficacy in the treatment of AECOPD,and it can effectively improve the symptoms and signs,lung blood oxygen supply and airway dyspnea,and help to improve quality of life.