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| 中国南方地区鼻咽癌家族史危险因素的Meta分析 | |
| 引用本文： | 肖婷婷,林汉生. 中国南方地区鼻咽癌家族史危险因素的Meta分析[J]. 疾病控制杂志, 2006, 10(5): 499-501 |
| 作者姓名： | 肖婷婷 林汉生 |
| 作者单位： | 暨南大学医学院医学统计教研室,广东,广州,510632 |
| 摘 要： | 目的综合评价鼻咽癌家族史在中国南方地区鼻咽癌发病中的作用。方法应用Meta分析对国内9篇鼻咽癌家族史危险因素的病例对照研究文献进行定量综合分析。结果家族史危险因素单因素合并OR值为5.05,95%CI为3.49~7.32;多因素合并OR值为7.20,95%CI为4.52~11.46。结论遗传是中国南方地区人群鼻咽癌的重要危险因素,加权计算合并家族史OR值可以综合评价遗传因素的作用。 |
| 关 键 词： | 鼻咽肿瘤 危险因素 遗传学 |
| 文章编号： | 1008-6013（2006）05-0499-03 |
| 收稿时间： | 2005-11-20 |
| 修稿时间： | 2006-03-31 |
Meta-analysis of family history of risk factors associated with nasopharyngeal carcinoma in the southern China |
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| XIAO Ting-ting,LIN Han-sheng. Meta-analysis of family history of risk factors associated with nasopharyngeal carcinoma in the southern China[J]. Chinese Journal of Disease Control and Prevention, 2006, 10(5): 499-501 | |
| Authors: | XIAO Ting-ting LIN Han-sheng |
| Abstract: | Objective To evaluate the risk factors of family history of nasopharyngeal carcinoma in south of China.Methods The results of 9 studies on the family history in risk factors of nasopharyngeal carcinoma were analysed by Meta-analysis.Results The univariate and multivariate pooled OR value(95% CI) of NPC family history were 5.05(3.49,7.32),7.20(4.52,11.46) respectively.Conclusions Heredity was the important risk factor of nasopharyngeal carcinoma.Calculating the weighing mean of pooled OR values of family history could comprehensively appraise the effect of genetic risk factors in occurrence of the disease. |
| Keywords: | Nasopharyngeal neoplasms Risk factors Genetics |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |