Longitudinal studies on the egg drop syndrome 1976 (eds-76) in the fowl following experimental infection at 1-day-old

Following oral infection of 1-day-old chicks with egg drop syndrome - 1976 (EDS-76) virus (strain D61) lateral transmission of the virus was demonstrated throughout the rearing period. At point of lay, pullets previously infected at 1-day-old responded to EDS-76 inactivated vaccine given intramuscularly with a pronounced rise in haemagglutination inhibition antibody titre, but failed to respond to oral challenge with live virus. Egg production and shell quality were not affected following EDS-76 infection at 1-day-old, but egg weight was reduced and internal egg quality adversely affected.