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间歇性外斜视患者眼外肌的超微结构研究
引用本文:杜红,郭立云,李宪武. 间歇性外斜视患者眼外肌的超微结构研究[J]. 临床眼科杂志, 2011, 19(1): 12-15
作者姓名:杜红  郭立云  李宪武
作者单位:1. 昆明医学院第二附属医院眼科,650031
2. 云南省第二人民医院眼科
摘    要:
目的 研究间歇性外斜视患者眼外肌的超微结构,以期探讨间歇性外斜视的发病机制.方法 取8例间歇性外斜视患者、8例恒定性外斜视患者(间歇性外斜视恒定化)及8例同期角膜移植供体的健康人眼内直肌,常规HE染色后在光镜下观察并计算每例标本每100倍视野下肌纤维的含量;利用透射电镜观察8例间歇性外斜视患者与5例同期角膜移植供体的健...

关 键 词:间歇性外斜视  眼外肌

Ultrastructural study of extraocular muscule in intermittent exotropia
DU Hong,GUO Li-yun,LI Xian-wu. Ultrastructural study of extraocular muscule in intermittent exotropia[J]. Journal of Clinical Ophthalmology, 2011, 19(1): 12-15
Authors:DU Hong  GUO Li-yun  LI Xian-wu
Affiliation:DU Hong,GUO Li-yun,LI Xian-wu. Department of Ophthalmology,the Second Affiliated Hospital of Kunming Medical College,Yunnan Province 650021,China
Abstract:
Objective To observe the ultrastructure of extraocular muscle (EOM) in intermittent exotropia and discuss it's pathothogenesis.Methods Samples obtained from medial rectus of 8 patients intermittent exotropia,8 patients with constrant exotropia,and 8 corneal donors,were stained with HE,and then examined under light microscopy(LM) to observe the structure of extraocular muscle and count the number of the muscle fibers of each sample under 100×magnification;8 case of sample from medial rectus of patients with intermittent exotropia and 5 samles of medial rectus from corneal graft donors were studied under transmission electron microscopy(TEM).Results (1)Under light microscopy,the muscle fibers of medial rectus of patients with intermittent exotropia and constrant exotropia showed atrophied and myofibribs became thin. Arrangmental direction of myofibrils became disorder.The numer of the muscle fibers under100×magnification of the groups with intermittent exotropia and constrant exotropia was significantly fewer than that in the control group(P 0.05),and the number of the groups with intermittent exotropia was significantly fewer than in the constrant exotropia(P 0.05).Conclusion The pathologic abnormality was been found in the ultrastructure of extraocular muscle with intermittent exotropia,which could be a possible etiology and pathogenesis of intermittent exotropia.
Keywords:Intermittent exotropia  Extraocular muscule  
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