氯美扎酮联合吲哚美辛栓治疗慢性非细菌性前列腺炎／慢性盆腔疼痛综合征的研究

目的评价氯美扎酮联合吲哚美辛栓治疗以疼痛为主诉的慢性非细菌性前列腺炎／慢性盆腔疼痛综合征（CP／CPPS）的疗效。方法对符合CP／CPPS标准的180例患者随机分为吲哚美辛栓组、氯美扎酮联合吲哚美辛栓组及特拉唑嗪组，疗程4周。在治疗结束时进行疗效判定，疗效评价标准采用视觉模拟评分方法。结果中途退出7例，173例患者进行了疗效评价，联合治疗组症状改善总有效率与吲哚美辛栓组（x^2=3．87，P〈0．05）和特拉唑嗪组（x^2=6．82，P〈0．01）相比疗效差异有统计学意义。治疗过程中无严重不良反应发生。结论氯美扎酮联合吲哚美辛栓可作为CP／CPPS疼痛患者的一种有效治疗手段。

Chlormezanone combined with indometacin suppositories for the treatment of chronic prostatitis/chronic pelvic pain syndrome

Objective To evaluate the clinical efficacy of chlormezanone combined with indometacin suppositories in the treatment of chronic prostatitis/ehronic pelvic pain syndrome （CP/CPPS）. Methods A total of 180 patients with CP/CPPS were randomly divided into three groups including indometacin suppositories group, chlormezanone plus indometacin suppositories group and telazuoqin group, in which the patients received corresponding treatments for 4 weeks. Visual analogue scales （ VAS ） was used to evaluate the curative effects after the treatment. Results The total effective rate in chlormezanone plus indometacin suppositories group was significantly higher than that in the indometacin suppositories group （ X2 = 3.87, P 〈 0.05 ） and the telazuoqin group （ x^2 = 6.82, P 〈 0. 01 ） respectively. There were no serious side effects during the therapy. Conclusion Chlormezanone combined with indometacin suppositories is highly effective for CP/CPPS.