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| 同型半胱氨酸检测在糖尿病肾病中的意义 | |
| 引用本文： | 陈峥,陈卫东,常保超,史菲菲. 同型半胱氨酸检测在糖尿病肾病中的意义[J]. 实用全科医学, 2008, 6(11): 1107-1108 |
| 作者姓名： | 陈峥 陈卫东 常保超 史菲菲 |
| 作者单位： | 安徽省蚌埠医学院第一附属医院肾病科,233004 |
| 基金项目： | 安徽省教育厅自然科学基金项目(2005KJ290) |
| 摘 要： | 目的探讨同型半胱氨酸在糖尿病肾病发生发展中的临床意义。方法选择134例2型糖尿病患者，并根据尿白蛋白排泄率及血肌酐水平将其分为单纯糖尿病组、早期糖尿病肾病组、临床糖尿病肾病组和肾衰竭组，30例健康体检者为正常对照组，检测其血同型半胱氨酸水平。采用SPSS13．0统计软件进行分析。结果各组血浆同型半胱氨酸水平相比较，糖尿病合并肾病组显著高于单纯糖尿病组，并随糖尿病肾病患者肾脏损伤程度的加重而升高，每两组间相比差异有统计学意义（P〈0．01）。结论高同型半胱氨酸血症是糖尿病患者出现肾脏损害的危险因素，血浆同型半胱氨酸水平可作为糖尿病肾病病情监测的有效指标。 |
| 关 键 词： | 同型半胱氨酸 2型糖尿病 糖尿病肾病 |
Determination of Homocysteine in Patients with Type 2 Diabetic Nephropathy and its Clinical Significance |
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| CHEN Zheng,CHEN Wei-dong,CHANG Bao-chao,et al.. Determination of Homocysteine in Patients with Type 2 Diabetic Nephropathy and its Clinical Significance[J]. Applied Journal Of General Practice, 2008, 6(11): 1107-1108 | |
| Authors: | CHEN Zheng CHEN Wei-dong CHANG Bao-chao et al. |
| Affiliation: | CHEN Zheng,CHEN Wei-dong,CHANG Bao-chao,et al.Department of Nephropathy,the First Affilated Hospital of Bengbu Medical College,Anhui 233004,China |
| Abstract: | Objective To discuss the relationship between homocysteine and type 2 diabetic complicated with diabetic nephropathy.Methods 134 patients with type 2 diabetic were divided into normal proteinuria group(30 cases),microalbuminuria group(35 cases),clinical proteinuria group(38 cases) and chronic renal failure group(31 cases) according to 24 h urinary albumin excretion rate and serum creatinine.30 normal persons were chosen in normal control group.Then homocysteine was detected with cyclophorase method.Results ... |
| Keywords: | Homocysteine Type 2 diabetic Diabetic nephropathy |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |