原发性肝癌根治切除后肝动脉和／或门静脉插管化疗预防肝癌复发

目的：探讨原发性肝癌根治切除后肝动脉和／或门静脉插管皮下药物泵对肝癌复发的预防效果。方法：回顾性分析1995年6月－2000年4月根治性切除的原发性肝癌患者49例，其中并行肝动脉和门静脉插管12例（1组），单纯肝动脉插管8例（II组），单纯门静脉插管15例（Ⅲ组），14例未插管（Ⅳ组），随访6个月－5年，对结果进行比较，结果：Ⅰ，Ⅱ，Ⅲ组1年复发率低于Ⅳ组，而1圻生态率各组间无差异，Ⅰ，Ⅱ组3年复发率低于Ⅳ组，3年生存率也高于Ⅳ组，而5年复发率与生存率无差异，Ⅰ，Ⅱ，Ⅲ组比较1，3，5年复发率与生存率无明显差异，结论：原发性肝癌术后行肝动脉和／或门静脉插管皮下置药物泵痢便，安全，是预防肝癌复发的有效手段。

HAI and/or PVI after radical resection of primary hepatic carcinoma for preventing tumor recurrence

Objective To study the effect of HAI and/or PVI after radical resection of hepatocellular carcinoma (HCC) for preventing recurrence.Methods From Jun. 1995 to Apr. 2000, 49 patients with HCC were undergone radical tumor resection. They were divided into 4 group: the treatment combined with HAI and PVI was given in group I(12 cases), HAV alone in group II (8 cases); PVI alone in group III (15 cases); nothing in group IV (14 cases). All patients were followed up for 6 months to 5 years. Results Recurrence rate at one year didn't show significantly lower in group I, II and III than that in grou IV. Survival rate in one year showed no significant difference in 4 groups. Recurrence rate in three years was significantly lower in group I and II than that in group IV. Survival rate in three years was significantly higher in group I and II than that in group IV. Recurrence rate and survival rate in five years showed no significante difference in four groups. Conclusions The treatment of radical resection of HCC combined with HAI and/or PVI is simple and safe. It is an useful method for preventing tumor recurrence.