| 血液灌流对维持性血液透析患者血浆瘦素及营养状况的影响 |
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| 引用本文： | 何平,杜丰,杨旭,李德天.血液灌流对维持性血液透析患者血浆瘦素及营养状况的影响[J].中国全科医学,2010,13(8):817-818. |
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| 作者姓名： | 何平 杜丰 杨旭 李德天 |
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| 作者单位： | 中国医科大学附属盛京医院肾内科,辽宁省沈阳市,110004 |
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| 摘 要： | 目的 探讨血液灌流(HP)对维持性血液透析患者血浆瘦素(Leptin)及营养状况的影响.方法 将48例慢性肾衰竭(CRF)透析患者随机分成两组,血液灌流(HP)联合血液透析(HD)治疗组(HP+HD 组)24例,单纯HD治疗组(HD组)24例,分别于治疗前后测定两组患者的血浆瘦素(Leptin)、前清蛋白(PA)、转铁蛋白(TRF)、清蛋白(Alb)及血红蛋白(Hb)的水平,对比两组的测定结果并分析各指标间的相关性.结果 治疗前两组患者的血浆Leptin、PA、TRF、Alb及Hb的水平间差异均无统计学意义(P＞0.05),治疗后 HP+HD组患者的血浆Leptin水平明显降低,各营养指标明显改善,与HD组相比差异有统计学意义(P＜0.05);血浆Leptin水平与PA、Alb水平呈负相关(P＜0.05).结论 HP能有效清除Leptin,改善患者的营养状况;PA可能是反映早期CRF患者营养状况的指标之一.
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| 关 键 词： | 血液灌流 肾透析 瘦素 营养不良 |
Effects of Hemoperfusion on Serum Leptin and Nutritional Status in Maintenance Hemodialysis Patients |
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| HEPing,DUFeng,YANGXu,etal.Effects of Hemoperfusion on Serum Leptin and Nutritional Status in Maintenance Hemodialysis Patients[J].Chinese General Practice,2010,13(8):817-818. |
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| Authors: | HEPing DUFeng YANGXu etal |
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| Institution: | HE+Ping,DU+Feng,YANG+Xu,et+al.Department+of+Nephrology,Shengjing+Hospital+of+China+Medical+University,Shenyang+110004,China |
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| Abstract: | Objective To research the effects of hemoperfusion (HD) on serum leptin and nutritional status in maintenance hemodialysis (MH) patients.Methods Forty-eight MH patients were divided randomly into groups HP and HP+HD,24 in each.Serum leptin,pre-albumin(PA),transferrin(TRF),albumin(Alb) and haemoglobin (Hb) were detected in 2 groups before treatment and after 3 months of treatment.The results were determined to analyze the correlation between the indexes.Results There was not significant difference in Leptin,... |
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| Keywords: | Hemoperfusion Renal dialysis Leptin Malnutrition |
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