亚甲蓝染色法乳腺癌前哨淋巴结活检术100例分析

目的 探讨分析前哨淋巴结活检术在乳腺癌手术中的应用价值及存在的问题.方法 回顾分析皖南医学院弋矶山医院甲乳外科2012年1月-2013年12月确诊为早期乳腺癌并使用亚甲蓝染色法行前哨淋巴结活检的100例女性患者的病例资料,对前哨淋巴结及腋窝淋巴结的病理结果进行对比分析.结果 100例患者中,92例可见SLN,成功率92％,共检出前哨淋巴结217个,每例1～6枚,平均2.4枚,92例均行ALND.其中,SLN阴性ALN阴性的58例,SLN阴性ALN阳性的4例,SLN阳性ALN阳性的30例,所有患者没有出现过敏反应.SLNB的假阳性率为0,假阴性率为11.8％,灵敏度88.3％,特异度100％,诊断符合率为95.7％.结论 SLNB在早期乳腺癌手术中较传统的ALND有明显的优势,对于SLN阴性的病例可不行ALND.

Methylene blue staining method in the sentinel lymph node biopsy in 100 cases of early breast cancer

Objective To analysis the application value and the existing problems of sentinel lymph node biopsy in breast cancer surgery.Methods Pathological findings were retrospectively analysised in 100 female cases of breast cancer,who were diagnosed with early breast cancer and used blue dye in sentinel lymph node biopsy.Results Among 100 cases,92 cases were found SLNS,that the detected rate was 92％.Detected 217 sentinel lymph node,every case has 1 to 6 node,with the average of 2.4.Nintg-two cases were performed ALND.Among them,the SLNS negative detected 58 cases of ALN feminine,SLNS negative ALN detected positive 4 cases,30 cases of SLNS positive ALN positive detected.All of the patients did not appear allergic reaction.SLNB false positive rate of O,the false negative rate was 11.8％,sensitivity 88.3％,specific degree of 100％,the diagnostic coincidence rate was 95.7％.Conclusions Compared with the conventional axillary lymph node dissection,the sentinel lymph node biopsy has obvious advantages in early breast cancer surgery.For the cases of sentinel lymph node negative,there was no necessary to do the axillary lymph node dissection.