The effect of vaginal administration of various doses of prostaglandin E2 gel on cervical ripening and induction of labor |
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| Authors: | G R Graves T F Baskett J H Gray E R Luther |
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| Affiliation: | 1. Department of Oromaxillofacial Head and Neck Oncology, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China;2. School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China;3. Department of Oral and Maxillofacial Surgery, Qingdao Municipal Hospital, Shandong, China |
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| Abstract: | ![]()
Eighty patients with a Bishop score of less than or equal to 4 were randomly administered vaginal triacetin gel containing placebo or prostaglandin E2 in 1, 2, and 3 mg doses. Twelve to sixteen hours later, those not in labor underwent oxytocin induction. Increasing doses of prostaglandin were effective in ripening the cervix, and the higher doses were associated with significant success in inducing labor. |
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