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| CO2激光微创手术治疗早期喉癌 | |
| 引用本文： | 刘吉祥,王林,杜建群. CO2激光微创手术治疗早期喉癌[J]. 中国中西医结合耳鼻咽喉科杂志, 2008, 16(5): 349-352 |
| 作者姓名： | 刘吉祥 王林 杜建群 |
| 作者单位： | 1. 天津市人民医院耳鼻咽喉科,300121 2. 天津市第一中心医院耳鼻咽喉科 |
| 摘 要： | 目的观察CO2激光微创手术治疗早期喉癌的安全性、远期疗效。方法回顾性分析1999年10月至2007年5月接受CO2激光显微外科手术治疗91例声门型喉癌（Tis9例，pTla 45例，pTlb 25例，和PT2 12例），对其中20例患者术后创面前、后、中上、中下及深部切缘组织同时进行常规病理切片镜检及PCNA免疫组织化学测定。结果依照Kaplan—Meier方法计算5年整体生存率为92．72％，无瘤生存率84．62％。采用3mm安全界100个切缘标本中，发现癌细胞残留3个（2名患者）。结论早期喉癌CO2激光微创手术，不仅损伤小，愈合快，而且远期疗效好，采用3mm安全界可获得安全切缘。 |
| 关 键 词： | 喉肿瘤 激光手术 增殖细胞核抗原 |
Carbon dioxide laser microsurgery for early glottic carcinoma |
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| LIU Jixiang,WANG Lin,BU Jianqun. Carbon dioxide laser microsurgery for early glottic carcinoma[J]. Chinese Journal of Otorhinolaryngology of Integrated Traditional and Western Medicine, 2008, 16(5): 349-352 | |
| Authors: | LIU Jixiang WANG Lin BU Jianqun |
| Affiliation: | LIU Jixiang WANG Lin DU Jianqun The Department of Otorhinolaryngology Head , Neck Surgery,The Tianjin People's Hospital,Yianjin 300121,China |
| Abstract: | Objective To investigate the oncologic efficacy and safety of transoral endoscopic CO2 laser surgery in early glottic carcinoma.Methods A retrospective study of 91 patients with glottic carcinoma(9 Tis,45 pTla,25 pTlb,and 12 pT2)treated from October 1999 to May 2007.The clinicopathology and the PCNA expression in 100 tissue' s specimen of 20 postoperative patients was studied.Results According to the Kaplan-Meier method,the 5 year overall survival and the diseasefree survival were 92.72% and 84.62% respecti... |
| Keywords: | Laryngeal neoplasms Laser surgery Proliferating cell nuclear antigen |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |