男性更年期综合征中医证型与性激素水平相关性研究

目的：探讨男性更年期综合征中医证型与性激素水平的相关性。方法：对562例男性更年期综合征中医辨证主要为肾阴虚证、肾阳虚证、心阴虚证、心阳虚证、心肾不交证、肝阴虚证、肝气郁结证的患者，均在就诊次日上午7～10点抽取空腹血6mL进行血清性激素测定。结果：562例调查对象总睾酮含量以肾阳虚证最低，与其他各证型比较差异有统计学意义（P〈0．01）。游离睾酮含量从低到高依次为肾阳虚证、肾阴虚证、心阳虚证、肝阴虚证、心阴虚证、心肾不交证、肝气郁结证，其中肾阳虚、。肾阴虚证、心阳虚证与其他各证型比较差异有统计学意义（P〈0．01或P〈0．05）。雌二醇含量以。肾阴虚证最高，其次是肝阴虚证，以肾阳虚证及心阳虚证含量较低，两者比较差异有统计学意义（P〈0．05）。孕酮以肝气郁结证含量最高，与其他各证型比较差异有统计学意义（P〈0．05）。PRL、LH、FSH值各组均数间比较无统计学意义（P〉0．05）。结论：男性更年期综合征中医各辨证分型与血清性激素水平的个别指标有一定的相关性，为中医证型的客观化及提高中医辨证治疗男性更年期综合征的临床水平提供确切的理论依据。

A Study on Relativity between Traditional Chinese Medicine Syndromes of Male Climacteric Syndrome and Levels of the Sex Hormones

Objective： To research the relativity between Traditional Chinese Medicine syndromes of male climacteric syndrome （MCS） and levels of the sex hormones. Methods ： The main Types of syndrome of 562 patients are deficiency of kidney - Yin, deficiency of kidney - Yang, deficiency of heart - Yin, deficiency of heart - Yang, disharmony between heart and kidney, deficiency of liver - Yin and stagnation of liver - Qi. All the patients were drawn 6 ml blood for serum sex hormones test on an empty stomach between eight and ten a. m. Re- suits ： Total testosterone of the patients with deficiency of kidney - Yang is lowest than that of other types. There are statistical differences between deficiency of kidney - Yang and other types （P 〈 0. 01 ）. All the types with the level of total testosterone from the lower to higher are deficiency of kidney - Yang, deficiency of kidney - Yin, defi- ciency of heart - Yang, deficiency of liver - Yin, deficiency of heart - Yin, disharmony between heart and kidney and stagnation of liver - Qi. There are statistical differences between deficiency of kidney - Yang, deficiency of kidney - Yin, deficiency of heart - Yang and the other types （ P 〈 0. 01 or P 〈 0. 05 ）. The type with highest level of estradiol is deficiency of kidney - Yin. The higher is deficiency of liver - Yin. The types with lower level of es- tradiol are deficiency of kidney - Yang and deficiency of heart - Yang. There are statistical differences between them （ P 〈 0. 05 ）. The type with highest level of progestin is stagnation of liver - Qi which has statistical differ- ences to others （P 〈 0. 05 ）. There are no significant differences between PRL, LH and FSH （P 〉 0. 05 ）. Conclusion： There is relativity between TCM Syndromes of male climacteric syndrome and individual sex hormones in- dex. It can provide the exact theoretical basis of objective of TCM and improving clinical treatment of male climacteric syndrome by TCM.