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冠心病患者胰岛素抵抗与肌钙蛋白I的关系
引用本文:匡永东,叶向阳,李星群,龚名,潘继豹. 冠心病患者胰岛素抵抗与肌钙蛋白I的关系[J]. 中国临床医学, 2002, 9(6): 647-648
作者姓名:匡永东  叶向阳  李星群  龚名  潘继豹
作者单位:温州医学院附属第三医院心血管内科,温州医学院附属第三医院心血管内科,温州医学院附属第三医院心血管内科,温州医学院附属第三医院心血管内科,温州医学院附属第三医院心血管内科 瑞安 325200,瑞安 325200,瑞安 325200,瑞安 325200,瑞安 325200
摘    要:
目的:研究冠心病患者胰岛素抵抗与肌钙蛋白I的关系。方法:用发光免疫法测定空腹胰岛素(FINS)及肌钙蛋白I(TnI),用1/(FINS×FPG)的自然对数作为胰岛素敏感指数(ISI),对ISI与TnI进行相关分析。结果:不稳定型心绞痛组及稳定型心绞痛组的ISI明显低于健康对照组,不稳定型心绞痛组的TnI明显高于其余两组,不稳定型心绞痛组的ISI与TnI呈负相关关系。结论:胰岛素抵抗与心肌损害存在一定内在联系。

关 键 词:冠心病 胰岛素抵抗 肌钙蛋白I 冠状动脉粥样硬化性心脏病 发光免疫法

The Correlation Analysis of Insulin Resistance and Troponin I in Coronary Artery Atherosclerosis
Kuang Yongdong Ye Xianyang Li Xingqun,et al.. The Correlation Analysis of Insulin Resistance and Troponin I in Coronary Artery Atherosclerosis[J]. Chinese Journal Of Clinical Medicine, 2002, 9(6): 647-648
Authors:Kuang Yongdong Ye Xianyang Li Xingqun  et al.
Abstract:
Objective: To study the relationship between insulin resistance and Troponin I (TnI) in coronary artery atherosclerosis. Methods: The level of fasting plasma insulin and TnI were determined by means of paramagnetic particle, chemiluminescent immunoassay. Insulin-sensitive index(ISI)was defined by the natural logarithmic value of the reverse of fasting serum glucose and insulin product, correlations between ISI and TnI was obtained by using linear regression analysis. Results:ISI in stable angina pectoris group and unstable angina pectoris group were lower than health group. TnI in UAP group was higher than other groups.There was a negative linear correlation of ISI and TnI in UAP group.Conclusion:There may be certain inner association between insulin resistance and the myocardial injury in unstable angina pectoris.
Keywords:Insulin resistance Troponin I Coronary artery atherosclerosis disease
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