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| 早产儿用面罩给氧后抗氧化水平的变化 | |
| 引用本文： | 胡春华,涂前慧,胡腊先,雷引娣. 早产儿用面罩给氧后抗氧化水平的变化[J]. 中国康复, 2002, 17(2): 92-93 |
| 作者姓名： | 胡春华 涂前慧 胡腊先 雷引娣 |
| 作者单位： | 430030,武汉,华中科技大学同济医学院附属同济医院儿科 |
| 摘 要： | 目的：了解早产患儿氧化应激反应能力，以指导临床合理用氧。方法：60例早产儿分为3组，AB2组均给氧治疗，C组不用氧。治疗前后监测3组血浆中谷胱甘肽（GSH）和丙二醛（MDA）值。结果：AB2组组血浆GSH含量均低于C组，给氧时间越长，氧浓度越高，GSH含量越低；AB2组MDA均高于C组，且随着氧浓度和给氧时间的增加而增高。结论：早产患儿对高氧暴露的反应能力低下，长时间高浓度的氧疗可使其抗氧化能力降低，即使在面罩给氧化和抗氧化的动态平衡也有改变，如产生的自由基超过机体的清除能力，机体将受到相应损害，故建立临床上应注意合理用氧。 |
| 关 键 词： | 早产儿 面罩给氧 抗氧化水平 谷胱甘肽 丙二醛 GSA MDA |
| 文章编号： | 1001-2001(2002)02-0092-02 |
| 修稿时间： | 2002-02-05 |
Change of Antioxidative Level in Prematures after Face-masked Oxygen Supply |
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| Hu Chunhua,Tu Qianhui,Hu Laxian,et al.. Change of Antioxidative Level in Prematures after Face-masked Oxygen Supply[J]. Chinese Journal of Rehabilitation, 2002, 17(2): 92-93 | |
| Authors: | Hu Chunhua Tu Qianhui Hu Laxian et al. |
| Affiliation: | Hu Chunhua,Tu Qianhui,Hu Laxian,et al.Department of Pediatrics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030 |
| Abstract: | Objective: To know the oxidative stress reaction of the prematures so as to guide the rational usage of oxygen. Methods: Sixty prematures were divided into 3 groups: groups A and B received the therapy of oxygen supply, while group C didn't received oxygen supply. Before and after treatment, GSH and MDA were monitored in the 3 groups. Results: In the groups A and B, the content of GSH was lower than in the control group in time and concentration dependent manners. The content of MDA in the groups A and B was higher than in the group C in time and concentration dependent manners. Conclusion: The prematures had a low reaction ability to high oxygen exposure. Long term oxygen therapy with high concentration could decrease the antioxidative ability. It was recommended to rationally supply oxygen clinically. |
| Keywords: | premature face masked oxygen supply antioxidative level |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |