黑地黄丸对慢性肾衰竭患者肾功能指标影响

目的：观察黑地黄丸对慢性肾衰竭患者肾功能指标的影响。方法：入选160例病例,采用前瞻性、随机、阳性药物平行对照方法进行临床试验,试验结束后观察患者血肌酐（Scr）、血尿素氮（BUN）、内生肌酐清除率（Ccr）等指标变化。结果：试验组治疗后血Scr水平低于治疗前,有统计学意义（P〈0.05）,试验组治疗后血Ccr水平高于治疗前,有高度统计学意义（P〈0.01）;两组治疗后比较血Scr水平与Ccr水平比较,差异有统计学意义（P〈0.05）;两组治疗后对血BUN、CO2-CP影响比较,差异无统计学意义（P〉0.05）。结论：黑地黄丸可降低患者Scr、Ccr,对BUN无影响。

Influence of Heidihuang Pill on Renal Index of Patients with Chronic Renal Failure

Objective：To observe the influence of Heidihuang Pill on renal index of patients with chronic renal failure. Methods： 160 cases were selected, using the prospective, randomized clinical trials and positive drug parallel contrast method. After the experiment, patients＇ serum creatinine （ Ser ）, bloodurea nitrogen （ BUN ）, endogenous creatinine clearance rate （ Ccr ） indicators were observed. Results ： The blood level of Scr in experimental group was lower than that before treatment, and there was statistically significant difference （ P〈0.05 ）. The blood level of Ccr in the experimental group after treatment was higher than that before treatment, and there was highly statistically significant difference （ P〈0.01 ）. Blood levels of Scr and Ccr comparison was statistically significant （ P〈0.05 ）. After treatment, the two groups＇ effects on blood BUN and CO2-CP had no statistically significant difference （ P〉0.05 ）. Conclusion ： Heidihuang Pill can reduce patients＇ Scr and Ccr, without any influence on BUN.