| 癌基因c-myc、Ha-ras在人肺鳞状细胞癌中的增强表达 |
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| 引用本文： | 齐上乐,范慕贞,赵成龙. 癌基因c-myc、Ha-ras在人肺鳞状细胞癌中的增强表达[J]. 中日友好医院学报, 1988, 0(4) |
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| 作者姓名： | 齐上乐 范慕贞 赵成龙 |
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| 作者单位： | 中日友好医院临床医学研究所生物化学室，中日友好医院临床医学研究所生物化学室，中日友好医院临床医学研究所生物化学室 |
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| 摘 要： | 本文初步研究了人肺鳞癌中c-myc及Ha-ras癌基因的表达。斑点杂交自显影密度分析的结果表明,人肺鳞癌总RNA中Ha-ras及c-myc基因的mRNA分别是正常人肺组织的32倍及10倍。这两种基因表达的增加在人肺恶性变中的作用,尚有待深入研究。
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| 关 键 词： | 癌基因 人肺鳞癌 |
ELEVATION OF EXPRESSION OF C-MYC AND HA-RAS ONCOGENES IN HUMAN SQUAMOUS LUNG CANCER |
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| Qi Shangle,et al. ELEVATION OF EXPRESSION OF C-MYC AND HA-RAS ONCOGENES IN HUMAN SQUAMOUS LUNG CANCER[J]. Journal of China-Japan Friendship Hospital, 1988, 0(4) |
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| Authors: | Qi Shangle et al |
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| Affiliation: | Department of Biochemistry |
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| Abstract: | Expression of c-myc and Ha-ras oncogenes was investigated preliminiarily in human squamous lung cancer. Densitometric analysis of the autoradiographic signal from dot blots indicated a 32 and 10 fold increase of the Ha-ras and c-myc mRNA in total RNA of-human squamous lung cancer tissue, respectively, as compared to those of normal, human lung. It remains to be determined whether the elevated expression of c-myc and Ha-ras are involved in the pathogenesis of human squamous lung cancer. |
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| Keywords: | oncogenes human squamous lung cancer |
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