| 急性白血病患者血清白细胞介素-2及T淋巴细胞亚群水平测定 |
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| 引用本文： | 杨俊文,贺付成,尹惠卿. 急性白血病患者血清白细胞介素-2及T淋巴细胞亚群水平测定[J]. 河南医学研究, 2000, 9(2) |
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| 作者姓名： | 杨俊文 贺付成 尹惠卿 |
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| 作者单位： | 郑州市儿童医院检验科 河南郑州 450053;河南医科大学一附院检验科 河南郑州 450052 |
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| 摘 要： | 目的 :探讨急性白血病 (AL)患者血清白细胞介素 2 (IL 2 )及血液T细胞亚群水平。方法 :采用酶联免疫吸附试验 (ELISA)及荧光免疫法测定 3 0例急性白血病 (AL)患者血清白细胞介素 2 (IL 2 )及血液T细胞亚群水平 ,并与对照组进行比较。结果 :AL患者血清IL 2含量显著低于对照组 (P <0 .0 1) ,T细胞亚群中CD+ 3 、CD+ 4均低于对照组水平 (P <0 .0 1) ,CD+ 8高于对照组水平 (P >0 .0 5 ) ,经治疗缓解患者IL 2 ,CD+ 3 、CD+ 4、CD+ 8达正常水平。结论 :IL 2和T细胞亚群可作为AL辅助诊断指标 ,为临床治疗提供实验依据。
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| 关 键 词： | 性白血病 白细胞介素-2 T-淋巴细胞亚群 |
Measurement of interleukin-2 and T lymphocytes subsets levels in acute leukaemia patients |
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| YANG Jun-wen,HE Fu-cheng,YIN Hui-qing. Measurement of interleukin-2 and T lymphocytes subsets levels in acute leukaemia patients[J]. Henan Medical Research, 2000, 9(2) |
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| Authors: | YANG Jun-wen HE Fu-cheng YIN Hui-qing |
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| Abstract: | Objective: To study the changes of interleukin 2(IL 2) and T cell subsets levels of acute leukaemia(AL) patients.Methods: The changes of IL 2 and T cell subsets levels of 30 acute AL patients were determined by using ELISA and fluorescence immunological method and the comparison between the original cases and the controlled group was also made.Results: It was revealed that IL 2,CD 3 and CD 4 T cells of the patients were significantly lower than those of the control group.CD 8 T cell was higher than that of the control group.IL 2,CD 4 and CD 8 T cells levels of the cured patients almost recovered to normal.Conclusion: IL 2,CD 3 and CD 4 T cell subsets can be used as the assitant index of diagnosis,and provide experimental basis for the clinic therapy. |
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| Keywords: | interleukin 2 T 1ymphocytes subsets acute leukaemia |
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