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影响马来丝虫对长爪沙鼠感染率因素的观察
引用本文:徐大刚,万启惠,李杰,聂文清,. 影响马来丝虫对长爪沙鼠感染率因素的观察[J]. 中国寄生虫学与寄生虫病杂志, 1998, 26(1): 38-41
作者姓名:徐大刚  万启惠  李杰  聂文清  
作者单位:上海第二医科大学寄生虫学教研室,遵义医学院寄生虫学教研室,大连医科大学寄生虫学教研室
摘    要:目的:探讨影响马来丝虫对长爪沙鼠感染率的因素。方法:用含马来丝虫感染期幼虫(L3)生理盐水感染长爪沙鼠,并分别加用抗生素、葡萄糖或培养液RPMI1640,观察接种鼠的存活率、感染率和感染度。结果:用含L3生理盐水组鼠存活率为80.9%,存活鼠感染率为60.5%,高感染度率为43.4%。加用抗生素组,鼠存活率为98.8%,存活鼠感染率为52.9%,高感染度率为30.6%。加用葡萄糖或RPMI1640组,鼠存活率(分别为98.0%和91.2%)、感染率(分别为68.8%和67.7%)和高感染度率(分别为50.0%和51.6%)均较高。长爪沙鼠感染马来丝虫浙江株(6代),存活鼠感染率和高感染度率均较贵州株(31代)高。结论:加用抗生素能提高感染鼠存活率,但其感染率和感染度降低。加用葡萄糖和RPMI1640,能提高感染鼠存活率、感染率和感染度。长爪沙鼠对浙江株(6代)较贵州株(31代)易感。

关 键 词:马来丝虫  长爪沙鼠  感染率  感染度

Observation on the factors influencing infection rate of Meriones unguiculatus with Brugia malayi]
Xu Dagang,Wan Qihui,Li Jie,Nie Wenqing. Observation on the factors influencing infection rate of Meriones unguiculatus with Brugia malayi][J]. Chinese Journal of Parasitology and Parasitic Diseases, 1998, 26(1): 38-41
Authors:Xu Dagang  Wan Qihui  Li Jie  Nie Wenqing
Affiliation:Department of Parasitology, Shanghai Second Medical University, Shanghai 200025.
Abstract:AIM: To explore the factors influencing the infection rate of M.unguiculatus with B.malayi. METHODS: The survival rate, infection rate and infection intensity were observed in M.unguiculatus infected with the infective larvae of B.malayi contained in normal saline, antibiotic, glucose or culture medium RPMI1640, respectively. RESULTS: The survival rate, infection rate and rate of infection intensity in normal saline group, antibiotic group, glucose group and RPMI1640 group were 80 9%,60 5%, and 43 4%; 98 8%,52 9% and 30 6%; 98 0%, 68 8% and 50 0%; 91 2%, 67 7% and 51 6%, respectively. The rate and the infection intensity were higher in the jirds infected with the 6th generation of Zhejiang strain than that with the 31st generation of Guizhou strain. CONCLUSION: The antibiotic was found to raise the living rate of the infected jirds, but reduce the infection rate and infection degree intensity; whereas glucose and culture medium RPMI1640 could raise the positive rate and the infectino. The jird was more susceptible to the 6th generation of Zhejiang strain than the 31st generation of Guizhou strain of B.malayi.
Keywords:Brugia malayi   Meriones unguiculatus   infection rate   infection degree
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