Identification of a novel HLA-DRB1*12 allele, DRB1*1218, in Chinese population |
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| Authors: | S.-Q. Gao,Z.-H. Deng,& Y.-P. Xu |
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| Affiliation: | Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, China |
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| Abstract: | Here, we report the identification of a novel human leukocyte antigen-DRB1*12 variant, DRB1*1218 allele, in a Chinese Han individual. The novel DRB1*12 variant allele differed from the closest allele DRB1*120201 by nucleotide 262 G>C (codon 59 GAG>CAG) missense mutation in exon 2, which resulted in an amino acid substitution of Glu>Gln. |
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| Keywords: | human leukocyte antigen intron novel allele sequence-based typing sequence-specific oligonucleotide |
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