SENCAR mouse skin tumors produced by promotion alone have A to G mutations in codon 61 of the c-rasHa gene |
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| Authors: | Sutter, Christian Greenhalgh, David A. Ueda, Masato Abhyankar, Suvarnarekha Ngai, Pakkay Hennings, Henry Schweizer, Jurgen Yuspa, Stuart H. Strickland, James E. |
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| Affiliation: | Research Program II, German Cancer Research Center D69-Heidelberg, Germany Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute Bethesda, MD 20892, USA |
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| Abstract: | ![]()
SENCAR mice, developed by selective breeding for high susceptibilityto skin carcinogenesis by initiation with 7, 12-dimethylbenz[a]anthraceneand promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA),form squamous papillomas in |
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