| 回盲肠间置幽门替代术动物模型的初步探讨 |
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| 引用本文： | 张集建,龙涛,郭光金,蒋登金,姜军,黄春霞,雷艳. 回盲肠间置幽门替代术动物模型的初步探讨[J]. 局解手术学杂志, 2005, 14(6): 361-363 |
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| 作者姓名： | 张集建 龙涛 郭光金 蒋登金 姜军 黄春霞 雷艳 |
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| 作者单位： | [1]第三军医大学基础医学部外科应用解剖与手术学教研室,重庆400038 [2]重庆工商大学理学院,重庆400067 [3]第三军医大学附属西南医院乳腺疾病科,重庆400038 |
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| 基金项目： | 全军医药卫生科研基金课题(01Z069) |
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| 摘 要： | 目的探讨回盲肠间置幽门替代术应用于动物胃肠道重建的可行性.方法将21头成年健康小型猪分为3组：假手术对照组（正常组）、B-I式胃大部切除组和远端胃大部切除带蒂回盲肠间置幽门替代手术组（回盲肠间置组）.术后观察对照动物的生存情况.结果手术后4个月,回盲肠间置组几乎未见呕吐、厌食及食量下降等现象;营养、精神状态及体力与正常组无甚差别;体重与术前无明显变化.而上述现象在B-I式组可见,且精神体力较差,体重较术前降低明显（P〈0.05）.结论回盲肠间置替代幽门重建消化道的动物模型可以借鉴.
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| 关 键 词： | 回盲瓣 幽门 疾病模型 动物 猪 |
| 文章编号： | 1672-5042(2005)06-0361-03 |
| 修稿时间： | 2005-07-28 |
Ileocecal interposition graft as substitute for pylorus in pigs |
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| ZHANG Ji-jian,LONG Tao,GUO Guang-jin,JIANG Deng-jin,JIANG Jun,HUANG Chun-xia. Ileocecal interposition graft as substitute for pylorus in pigs[J]. Journal of Regional Anatomy and Operative Surgery, 2005, 14(6): 361-363 |
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| Authors: | ZHANG Ji-jian LONG Tao GUO Guang-jin JIANG Deng-jin JIANG Jun HUANG Chun-xia |
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| Abstract: | Objective To evaluate the application of ileocecal interposition(II) graft as pylorus in gastrointestinal tract reconstruction.Methods Twenty-one minipigs were randomized into three groups: sham operation group,B-I group and II group.The qualities of life(QL) were compared after operation.Results In 4 months after operation,the side effects of the operation including vomit,loss of appetite and other metabolic and nutritional changes nearly disappeared in II group and the weight showed no difference with preoperation,while the side effects were always observed in B-I group and the weight was significantly less than that before operation(P<0.05).Conclusion The application of ileocecal interposition graft as pylorus in gastrointestinal tract reconstruction is feasible. |
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| Keywords: | ileocecal valve pylorus disease model animal pig |
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