Angiotensin converting enzyme gene polymorphism in type 2 diabetes mellitus

The aim of this study is the assessment of the association of human angiotensin-converting enzyme gene I/D polymorphism with type 2 diabetes in 155 diabetic patients and 139 healthy individuals. These polymorphism were studied using polymerase chain reaction. Angiotensin converting enzyme gene DD genotype associated with type 2 diabetes in overweight and obese patients and patients with normal total plasma cholesterol. There is also association of DD genotype with arterial hypertension and with myocardial infarction in type 2 diabetic patients.