| CD_4~+T细胞在哮喘中的作用 |
| |
| 引用本文： | 林群. CD_4~+T细胞在哮喘中的作用[J]. 医学综述, 2011, 17(12): 1789-1791 |
| |
| 作者姓名： | 林群 |
| |
| 作者单位： | 福建三明职业技术学院护理系,福建,三明,365000 |
| |
| 摘 要： | 哮喘是由多种细胞和细胞组分参与的呼吸道慢性炎症性疾患。其发病机制复杂,T淋巴细胞中CD4+T细胞在哮喘的发生发展中起重要作用。目前认为Th1/Th2失衡可导致Th2极化反应,并释放大量细胞因子产生呼吸道慢性炎症;CD4+CD25+调节性T细胞通过细胞接触和分泌细胞因子抑制哮喘的发展;Th17主要是通过分泌细胞因子参与炎性反应。
|
| 关 键 词： | 哮喘 Th1 Th2 Th17 |
CD4 +T Cell Role in Asthma |
| |
| LIN Qun. CD4 +T Cell Role in Asthma[J]. Medical Recapitulate, 2011, 17(12): 1789-1791 |
| |
| Authors: | LIN Qun |
| |
| Affiliation: | LIN Qun1,ZHU Ling2.(1.Department of Nursing,Fujian Sanming Vocational Technical College,Sanming 365000,2.Department of Immunology,Fujian Medical University,Fuzhou 350004,China) |
| |
| Abstract: | Asthma is a chronic airway inflammation disease,the mechanism of which is complex involving various cells and components.CD4 +T cell plays an important role in the occurrence of asthma.Present research sustains that the imbalance between Th1/Th2 may result in polarization of Th2,which then releases a great quantity of inflammatory cytokines;CD4 +CD25 +Tr can alleviate asthma through cell contact and secreting cytokine;Th17 is involved in inflammatory reaction by secreting relevant cytokine. |
| |
| Keywords: | Th1 Th2 Th17 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
