调强放射治疗剂量验证工具与方法

调强放射治疗广泛应用于肿瘤的治疗,其剂量分布在三维方向上与靶区高度适形.然而调强放疗的复杂射野、数据误差、算法误差及机器误差等因素可能会引起较大的剂量偏差,从而造成实际剂量与计划剂量不符,而严重的剂量不符可能会造成不必要的辐射事故.因此鉴于患者安全角度考虑,治疗计划在执行之前通常需要进行剂量验证,以确保患者治疗计划的安全实施,避免计划外的剂量照射.目前,临床上剂量验证的工具与方法有很多,包括指形电离室工具和热释光剂量仪工具等的点剂量验证法、半导体阵列工具和电离室阵列工具以及胶片工具等的二维剂量验证法、ArcCHECK工具和Delta4工具以及第三方软件工具等的三维剂量验证法等,对临床上常见的剂量验证工具和方法进行了综述.

Tools and methods of intensity-modulated radiation therapy dose verification

Intensity-modulated radiation therapy is widely used in the treatment of tumor,and the dose distribution highly conforms to tumor target area in three-dimension.However,the factors such as complex beam,data error,algorithm error and machine error may cause large dose deviation in intensity-modulated radiation therapy,which may lead to unnecessary radiation accident.Therefore,standing on the patients' safety point of view,dose verification is usually performed before executing the treatment plan in order to ensure the safe implementation of the treatment plan and to avoid un-planned irradiation dose.Currently,there are many tools and methods of dose verification in clinic,including point dose verification tools like finger-shaped ionization chamber and thermoluminescence dosimeter;two-dimensional dose verification tools like Mapcheck,MatriXX and films;three-dimensional dose verification tools like ArcCHECK,Delta4 and the third-party software.These common clinical dose verification methods are reviewed in this paper.